Literature DB >> 5260921

Evidence for a proposed initiation complex for protein synthesis in reticulocyte polyribosome profiles.

W Hoerz, K S McCarty.   

Abstract

Polysomes consisting of 40S ribosomal subunits attached to monosomes, disomes, trisomes, and tetrasomes have been isolated for the first time by the use of isokinetic sucrose density gradients. They are formed upon incubation of rabbit reticulocyte lysate in the presence of 10 mM NaF. It is proposed that these structures represent transient initiation complexes for protein synthesis.

Entities:  

Mesh:

Substances:

Year:  1969        PMID: 5260921      PMCID: PMC223451          DOI: 10.1073/pnas.63.4.1206

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  26 in total

1.  RESOLUTION OF AMINOACYL-TRANSFERRING ENZYMES FROM RAT LIVER BY MOLECULAR SIEVE CHROMATOGRAPHY.

Authors:  E GASIOR; K MOLDAVE
Journal:  J Biol Chem       Date:  1965-08       Impact factor: 5.157

2.  PHAGE f2 RNA-DIRECTED BINDING OF FORMYLMETHIONYL-TRNA TO RIBOSOMES AND THE ROLE OF 30S RIBOSOMAL SUBUNITS IN INITIATION OF PROTEIN SYNTHESIS.

Authors:  M Nomura; C V Lowry
Journal:  Proc Natl Acad Sci U S A       Date:  1967-09       Impact factor: 11.205

3.  The role of guanosine 5'-triphosphate in the initiation of peptide synthesis. 3. Binding of formylmethionyl-tRNA to ribosomes.

Authors:  T Ohta; S Sarkar; R E Thach
Journal:  Proc Natl Acad Sci U S A       Date:  1967-10       Impact factor: 11.205

4.  Protein-synthetic capacities of liver nuclear subfractions.

Authors:  K S McCarty; J T Parsons; W A Carter; J Laszlo
Journal:  J Biol Chem       Date:  1966-12-10       Impact factor: 5.157

5.  Resolution and fractionation of macromolecules by isokinetic sucrose density gradient sedimentation.

Authors:  K S McCarty; D Stafford; O Brown
Journal:  Anal Biochem       Date:  1968-08       Impact factor: 3.365

6.  Control of haemoglobin synthesis: distribution of ribosomes on the messenger RNA for alpha and beta chains.

Authors:  T Hunt; T Hunter; A Munro
Journal:  J Mol Biol       Date:  1968-08-28       Impact factor: 5.469

7.  The role of ribosomal subunits and 80-S monomers in polysome formation in an ascites tumour cell.

Authors:  B L Hogan; A Korner
Journal:  Biochim Biophys Acta       Date:  1968-11-20

8.  Hemoglobin synthesis in a cell-free system.

Authors:  P M Knopf; H M Dintzis
Journal:  Biochemistry       Date:  1965-07       Impact factor: 3.162

9.  Studies on the genesis of polyribosomes. I. Origin and significance of the subribosomal particles.

Authors:  W K Joklik; Y Becker
Journal:  J Mol Biol       Date:  1965-09       Impact factor: 5.469

10.  The mechanism of sodium fluoride and cycloheximide inhibition of hemoglobin biosynthesis in the cell-free reticulocyte system.

Authors:  S Y Lin; R D Mosteller; B Hardesty
Journal:  J Mol Biol       Date:  1966-10-28       Impact factor: 5.469

View more
  14 in total

1.  Functional redundancy of yeast proteins Reh1 and Rei1 in cytoplasmic 60S subunit maturation.

Authors:  K Mark Parnell; Brenda L Bass
Journal:  Mol Cell Biol       Date:  2009-05-11       Impact factor: 4.272

2.  Testing with puromycin and amino acyl tRNAs that limit the rate of peptide chain extension.

Authors:  L M Garrick; M D Garrick
Journal:  Mol Cell Biochem       Date:  1978-02-24       Impact factor: 3.396

3.  Occurrence of 40 S.polysomal complexes in polysome profiles of reticulocyte lysates.

Authors:  P W Tas; O H Martini
Journal:  Mol Biol Rep       Date:  1988       Impact factor: 2.316

4.  Use of purified polysomes from rabbit reticulocytes in a specific test for initiation factors.

Authors:  N H Lubsen; B D Davis
Journal:  Proc Natl Acad Sci U S A       Date:  1974-01       Impact factor: 11.205

5.  Factor-promoted dissociation of free ribosomes in a rabbit reticulocyte lysate system: inhibition and requirement for an energy source.

Authors:  S Mizuno; M Rabinovitz
Journal:  Proc Natl Acad Sci U S A       Date:  1973-03       Impact factor: 11.205

6.  Initial dipeptide formation in hemoglobin biosynthesis.

Authors:  R G Crystal; D A Shafritz; P M Prichard; W F Anderson
Journal:  Proc Natl Acad Sci U S A       Date:  1971-08       Impact factor: 11.205

7.  Aurintricarboxylic acid: inhibitor of initiation of protein synthesis.

Authors:  M L Stewart; A P Grollman; M T Huang
Journal:  Proc Natl Acad Sci U S A       Date:  1971-01       Impact factor: 11.205

8.  Effect of hypertonic conditions on protein synthesis in cells productively infected with simian virus 40.

Authors:  J M England; M K Howett; K B Tan
Journal:  J Virol       Date:  1975-11       Impact factor: 5.103

9.  Initiation of hemoglobin synthesis: comparison of model reactions that use artificial templates with those using natural messenger RNA.

Authors:  R G Crystal; W F Anderson
Journal:  Proc Natl Acad Sci U S A       Date:  1972-03       Impact factor: 11.205

Review 10.  Posttranscriptional control of gene expression in yeast.

Authors:  J E McCarthy
Journal:  Microbiol Mol Biol Rev       Date:  1998-12       Impact factor: 11.056

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.