Literature DB >> 5260919

Mechanism of proflavin mutagenesis.

A Sarabhai, H Lamfrom.   

Abstract

The mutagenic action of proflavin on bacteriophage T4 is greater in the presence of defective T4 ligase than in the presence of normal T4 ligase. This suggests that the persistence of single-strand breaks in DNA enhances proflavin mutagenesis.

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Year:  1969        PMID： 5260919      PMCID： PMC223449          DOI： 10.1073/pnas.63.4.1196

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  5 in total

1.  The structure of the DNA-acridine complex.

Authors:  L S LERMAN
Journal:  Proc Natl Acad Sci U S A       Date:  1963-01-15       Impact factor: 11.205

2.  General nature of the genetic code for proteins.

Authors:  F H CRICK; L BARNETT; S BRENNER; R J WATTS-TOBIN
Journal:  Nature       Date:  1961-12-30       Impact factor: 49.962

3.  A frame-shift mutation involving the addition of two base pairs in the lysozyme gene of phage t4.

Authors:  Y Okada; E Terzaghi; G Streisinger; J Emrich; M Inouye; A Tsugita
Journal:  Proc Natl Acad Sci U S A       Date:  1966-12       Impact factor: 11.205

4.  Enzymatic breakage and joining of deoxyribonucleic acid. II. The structural gene for polynucleotide ligase in bacteriophage T4.

Authors:  G C Fareed; C C Richardson
Journal:  Proc Natl Acad Sci U S A       Date:  1967-08       Impact factor: 11.205

5.  Change of a sequence of amino acids in phage T4 lysozyme by acridine-induced mutations.

Authors:  E Terzaghi; Y Okada; G Streisinger; J Emrich; M Inouye; A Tsugita
Journal:  Proc Natl Acad Sci U S A       Date:  1966-08       Impact factor: 11.205
  5 in total
  6 in total

1.  Ligase-defective bacteriophage T4. I. Effects on mutation rates.

Authors:  R E Koch; J W Drake
Journal:  J Virol       Date:  1973-01       Impact factor: 5.103

2.  Effect of acriflavine on UV-induced mutants of Fusarium species.

Authors:  U P Singh
Journal:  Mycopathol Mycol Appl       Date:  1973-07-31

3.  The effect of dose and time on the induction of genetic alterations in Saccharomyces cerevisiae by aminoacridines in the presence and absence of visible light irradiation in comparison with the dose-effect-curves of mutagens with other type of action.

Authors:  R Fahrig
Journal:  Mol Gen Genet       Date:  1976-03-22

4.  9-Aminoacridine mutagenesis of bacteriophage T4 intracellular DNA.

Authors:  S Altman; V Warner
Journal:  Mol Gen Genet       Date:  1975-07-10

5.  Specificity of deoxyribonucleic Acid intercalating compounds in the control of phenylalanine ammonia lyase and pisatin levels.

Authors:  L A Hadwiger; M E Schwochau
Journal:  Plant Physiol       Date:  1971-03       Impact factor: 8.340

6.  Reversion of frameshift mutations stimulated by lesions in early function genes of bacteriophage T4.

Authors:  H Bernstein
Journal:  J Virol       Date:  1971-04       Impact factor: 5.103
  6 in total

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