Literature DB >> 525991

Effectiveness of nafcillin, methicillin, and cephalothin in experimental Staphylococcus aureus endocarditis.

J Carrizosa, W D Kobasa, D Kaye.   

Abstract

Nafcillin, methicillin, and cephalothin (40 mg/kg every 6 h) were all effective in reducing the number of Staphylococcus aureus in vegetations in rabbits with endocarditis. Nafcillin and methicillin reduced the number of S. aureus at a significantly faster rate than did cephalothin. Nafcillin and methicillin also reduced titers of the S. aureus more rapidly than did cephalothin in vitro, both in broth and in rabbit serum.

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Year:  1979        PMID： 525991      PMCID： PMC352746          DOI： 10.1128/AAC.15.5.735

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  5 in total

1.  Pharmacology of cefazolin in patients with normal and abnormal renal function.

Authors:  M E Levison; S P Levison; K Ries; D Kaye
Journal:  J Infect Dis       Date:  1973-10       Impact factor: 5.226

2.  Chemotherapy of experimental streptococcal endocarditis. I. Comparison of commonly recommended prophylactic regimens.

Authors:  D T Durack; R G Petersdorf
Journal:  J Clin Invest       Date:  1973-03       Impact factor: 14.808

3.  Antibiotic synergism in enterococcal endocarditis.

Authors:  J Carrizosa; D Kaye
Journal:  J Lab Clin Med       Date:  1976-07

4.  IN VITRO AND IN VIVO LABORATORY EVALUATION OF CEPHALOGLYCIN AND CEPHALORIDINE.

Authors:  W E WICK; W S BONIECE
Journal:  Appl Microbiol       Date:  1965-03

5.  Treatment of experimental Staphylococcus aureus endocarditis: comparison of cephalothin, cefazolin, and methicillin.

Authors:  J Carrizosa; J Santoro; D Kaye
Journal:  Antimicrob Agents Chemother       Date:  1978-01       Impact factor: 5.191
  5 in total
  4 in total

1.  Perioperative antibiotic prophylaxis in cardiovascular surgery: a prospective randomized comparative trial of cefazolin versus ceftriaxone.

Authors:  M Soteriou; F Recker; S Geroulanos; M Turina
Journal:  World J Surg       Date:  1989 Nov-Dec       Impact factor: 3.352

2.  Methicillin distribution in serum and extravascular fluid and its relevance to normal and damaged heart valves.

Authors:  F M Gengo; J J Schentag
Journal:  Antimicrob Agents Chemother       Date:  1981-05       Impact factor: 5.191

3.  Rate of methicillin penetration into normal heart valve and experimental endocarditis lesions.

Authors:  F M Gengo; J J Schentag
Journal:  Antimicrob Agents Chemother       Date:  1982-03       Impact factor: 5.191

4.  Penicillin therapy of experimental endocarditis induced by tolerant Streptococcus sanguis and nontolerant Streptococcus mitis.

Authors:  F D Lowy; E G Neuhaus; D S Chang; N H Steigbigel
Journal:  Antimicrob Agents Chemother       Date:  1983-01       Impact factor: 5.191
  4 in total

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