Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Evidence for one functional phenylalanyl-tRNA binding site on the 30S ribosomal subunit.

Literature DB >> 5256228

Evidence for one functional phenylalanyl-tRNA binding site on the 30S ribosomal subunit.

Abstract

NH(2) terminal analysis of polyphenylalanine formed from 30S subunit-bound (14)C-phenylalanyl-tRNA suggests that there is only one site in a 30S subunit for specific binding of phenylalanyl-tRNA. Assuming that no movement of the bound phenylalanyl-tRNA takes place during association of 30S subunits with 50S ribosomal subunits, the binding site of the 30S ribosomal subunit corresponds to site 2 (-NH(2) side with respect to the growing polypeptide chain) of the two binding sites of 70S ribosomes.

Entities: Chemical Species

Mesh：

Substances：

Year: 1969 PMID： 5256228 PMCID： PMC277826 DOI： 10.1073/pnas.62.2.498

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

15 in total

1. THE EFFECT OF POLYAMINES AND OF POLY U SIZE ON PHENYLALANINE INCORPORATION.

Authors: R G Martin; B N Ames
Journal: Proc Natl Acad Sci U S A Date: 1962-12 Impact factor: 11.205

2. Translation of the genetic message. VII. Role of initiation factors in formation of the chain initiation complex with Escherichia coli ribosomes.

Authors: K Iwasaki; S Sabol; A J Wahba; S Ochoa
Journal: Arch Biochem Biophys Date: 1968-05 Impact factor: 4.013

1. Dissociation of N(2) Gas-induced Monomeric Ribosomes and Functioning of the Derived Subunits in Protein Synthesis in Pea.

Authors: C Y Lin; J L Key
Journal: Plant Physiol Date: 1971-11 Impact factor: 8.340

1 in total

Evidence for one functional phenylalanyl-tRNA binding site on the 30S ribosomal subunit.

1. THE EFFECT OF POLYAMINES AND OF POLY U SIZE ON PHENYLALANINE INCORPORATION.

2. Translation of the genetic message. VII. Role of initiation factors in formation of the chain initiation complex with Escherichia coli ribosomes.

3. The initial phase in the polyuridylic acid-directed polymerization of phenylalanine.

4. Role of protein factor in the functional binding of ribosomes to natural messenger RNA.

5. Comparative studies on specific and nonspecific binding of transfer ribonucleic acid to ribosomes.

6. On the nature of two ribosomal sites for specific sRNA binding.

7. Inhibition by sparsomycin and other antibiotics of the puromycin-induced release of polypeptide from ribosomes.

8. Regulatory mechanisms and protein synthesis. X. Codon recognition on 30 S ribosomes.

9. Binding of specific sRNA to 30S subunits--comparison with the binding to 70S ribosomes.

10. RNA CODEWORDS AND PROTEIN SYNTHESIS. THE EFFECT OF TRINUCLEOTIDES UPON THE BINDING OF SRNA TO RIBOSOMES.

1. Dissociation of N(2) Gas-induced Monomeric Ribosomes and Functioning of the Derived Subunits in Protein Synthesis in Pea.