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Literature DB >> 524926

Effects of essential fatty acid deficiency on various functions of the rat erythrocyte membrane.

H Böhles, J F Nicholson, W C Heird, W Fekl.

Abstract

Various membrane transport functions have been studied in erythrocytes from essential fatty acid (EFA) deficient rats in order to determine whether or not functional abnormalities induced by documented EFA-deficiency of the membrane could be demonstrated. No differences were found between EFA deficient and control cells with respect to mean values for osmotic resistance or intracellular sodium and potassium concentrations. However, uptake of leucine by EFA deficient erythrocytes was significantly greater than that of control erythrocytes. Kinetic studies suggest that EFA deficiency enhances the passive diffusion component of this transport.

Entities: Chemical Disease Species

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Year: 1979 PMID： 524926 DOI： 10.1007/BF02023725

Source DB: PubMed Journal: Z Ernahrungswiss ISSN： 0044-264X

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References

13 in total

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Authors: E J Harris; K van Dam
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Effects of essential fatty acid deficiency on various functions of the rat erythrocyte membrane.

1. MIGRATION OF AMINO ACIDS ACROSS THE MEMBRANE OF THE HUMAN ERYTHROCYTE.

2. The study of steady-state concentrations of internal solutes of mitochondria by rapid centrifugal transfer to a fixation medium.

3. Nutrition classics from The Journal of Biological Chemistry 82:345-67, 1929. A new deficiency disease produced by the rigid exclusion of fat from the diet.

4. Blood lipid alterations in infants receiving intravenous fat-free alimentation.

5. Effect of essential fatty acid deficiency on amino acid uptake by the small intestine of rats.

6. Changes of total water and sucrose space accompanying induced ion uptake or phosphate swelling of rat liver mitochondria.

7. Essential fatty acid deficiency in an infant receiving prolonged parenteral alimentation.

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