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Literature DB >> 5243015

Rubidomycin in acute leukaemia in adults.

Abstract

In a preliminary study rubidomycin was found capable of inducing remission in adults with acute leukaemia, the remission rate in acute myeloblastic leukaemia comparing favourably with that achieved with previous forms of therapy. Marrow aplasia and cardio-toxicity occurred in a number of patients. Supportive measures during the former and early recognition by frequent electrocardiography can do much to mitigate these toxic effects.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1968 PMID： 5243015 PMCID： PMC1986219 DOI： 10.1136/bmj.3.5612.227

Source DB: PubMed Journal: Br Med J ISSN： 0007-1447

2 in total

1. Acute lymphoblastic leukaemia treated with a combination of prednisone, vincristine, and rubidomycin. Value of pathogen-free rooms.

Authors: G Mathé; M Hayat; L Schwarzenberg; J L Amiel; M Schneider; A Cattan; J R Schlumberger; C Jasmin
Journal: Lancet Date: 1967-08-19 Impact factor: 79.321

2. [Trial of treatment of acute lymphoblastic and myeloblastic leukemias by a new antibiotic: rubidomycin (RP 13,057). Study of 61 cases].

Authors: J Bernard; C Jacquillat; M Boiron; Y Najean; M Seligmann; J Tanzer; M Weil; P Lortholary
Journal: Presse Med Date: 1967-04-22 Impact factor: 1.228

2 in total

16 in total

1. Inhibition of adriamycin cardiotoxicity by acetyldaunomycin.

Authors: G Zbinden
Journal: Experientia Date: 1975-09-15

Review 2. Antineoplastic and immunosuppressive drugs. 3. Adverse effects and therapeutic problems.

Authors: M D Cridland
Journal: Drugs Date: 1972 Impact factor: 9.546

Review 3. Cancer chemotherapy--the first twenty-five years.

Authors: R B Scott
Journal: Br Med J Date: 1970-10-31

4. [Clinico-pharmacologic, cytochemical and Feulgen photometric studies in adult undifferentiated cell leukemias under combination chemotherapy with vincristine, daunorubicine and prednisone].

Authors: P Obrecht; H Merker; H H Hennekeuser; G Meuret; M Westerhausen; A Simon
Journal: Klin Wochenschr Date: 1970-11-01

Rubidomycin in acute leukaemia in adults.

1. Acute lymphoblastic leukaemia treated with a combination of prednisone, vincristine, and rubidomycin. Value of pathogen-free rooms.

2. [Trial of treatment of acute lymphoblastic and myeloblastic leukemias by a new antibiotic: rubidomycin (RP 13,057). Study of 61 cases].

1. Inhibition of adriamycin cardiotoxicity by acetyldaunomycin.

Review 2. Antineoplastic and immunosuppressive drugs. 3. Adverse effects and therapeutic problems.

Review 3. Cancer chemotherapy--the first twenty-five years.

4. [Clinico-pharmacologic, cytochemical and Feulgen photometric studies in adult undifferentiated cell leukemias under combination chemotherapy with vincristine, daunorubicine and prednisone].

5. Suppression of adjuvant arthritis by a new cytotoxic compound, rubidomycin.

6. Daunorubicin in acute leukaemia.

7. Treatment of acute leukemia and malignant lymphoma with (2"R)-4'-O-tetrahydropyranyladriamycin.

Review 8. Doxorubicin-Induced Cardiomyopathy in Children.

9. Adriamycin in the treatment of acute leukaemia.

10. Adriamycin and daunorubicin inhibition of mutant T4 DNA polymerases.