Literature DB >> 5241408

Irreversible enzyme inhibitors. CXIX. Active-site-directed irreversible inhibitors of dihydrofolic reductase with tissue specificity derived from 2,4,6-triaminopyrimidine with a terminal sulfonyl fluoride at the 5 position.

B R Baker, R B Meyer.   

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Year:  1968        PMID： 5241408     DOI： 10.1021/jm00309a018

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  2 in total

1.  Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue.

Authors:  Wentao Chen; Jiajia Dong; Lars Plate; David E Mortenson; Gabriel J Brighty; Suhua Li; Yu Liu; Andrea Galmozzi; Peter S Lee; Jonathan J Hulce; Benjamin F Cravatt; Enrique Saez; Evan T Powers; Ian A Wilson; K Barry Sharpless; Jeffery W Kelly
Journal:  J Am Chem Soc       Date:  2016-06-02       Impact factor: 15.419

Review 2.  Docking covalent targets for drug discovery: stimulating the computer-aided drug design community of possible pitfalls and erroneous practices.

Authors:  Abdul-Quddus Kehinde Oyedele; Abdeen Tunde Ogunlana; Ibrahim Damilare Boyenle; Ayodeji Oluwadamilare Adeyemi; Temionu Oluwakemi Rita; Temitope Isaac Adelusi; Misbaudeen Abdul-Hammed; Oluwabamise Emmanuel Elegbeleye; Tope Tunji Odunitan
Journal:  Mol Divers       Date:  2022-09-04       Impact factor: 3.364
  2 in total

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