Literature DB >> 522514

Absorption and metabolism of naphthalene and benzo(a)pyrene in the rat jejunum in situ.

K W Bock, U C von Clausbruch, D Winne.   

Abstract

Naphthalene or benzo(a)pyrene (100 nmol) was instilled into the closed rat intestinal loop in situ and the appearance of the free compound and its metabolites was determined in portal blood. Naphthalene appeared mostly unchanged in blood whereas benzo(a)pyrene was extensively metabolized by mucosal cells. The results suggest that absorption and metabolism are competing processes in the gut.

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Year:  1979        PMID： 522514

Source DB:  PubMed          Journal:  Med Biol        ISSN： 0302-2137


  4 in total

1.  Naphthalene distribution in tissues of laying pullets, swine, and dairy cattle.

Authors:  G R Eisele
Journal:  Bull Environ Contam Toxicol       Date:  1985-04       Impact factor: 2.151

2.  Role of the lymphatic system in the transport of absorbed 7,12-dimethylbenzanthracene in the rat.

Authors:  J M Laher; J A Barrowman
Journal:  Lipids       Date:  1987-03       Impact factor: 1.880

Review 3.  Naphthalene--an environmental and occupational toxicant.

Authors:  Ralf Preuss; Jürgen Angerer; Hans Drexler
Journal:  Int Arch Occup Environ Health       Date:  2003-08-15       Impact factor: 3.015

4.  Bioavailability and biotransformation of benzo(a)pyrene in an isolated perfused In situ catfish intestinal preparation.

Authors:  K M Kleinow; M O James; Z Tong; C S Venugopalan
Journal:  Environ Health Perspect       Date:  1998-03       Impact factor: 9.031
  4 in total

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