| Literature DB >> 521817 |
S P Gunasekera, M M Badawi, G A Cordell, N R Farnsworth, M Chitnis.
Abstract
The anticancer activity of the roots of Ervatamia heyneana (Apocynaceae) was found to be due principally to the known alkaloid, camptothecin (1). The closely related, but less active, 9-methoxycamptothecin (2) was also obtained. This is the first reported isolation of these biogenetically interesting alkaloids from the indole alkaloid rich Apocynaceae.Entities:
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Year: 1979 PMID： 521817 DOI： 10.1021/np50005a006
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050