Literature DB >> 5213700

Leukocyte alkaline phosphatase: electrophoretic variants associated with chronic myelogenous leukemia.

J C Robinson, J E Pierce, D P Goldstein.   

Abstract

Starch-gel electrophoresis of leukocyte alkaline phosphatases, rendered soluble by treating normal leukocytes with butanol, revealed three electrophoretic variants of the enzyme. The phosphatases in similarly prepared extracts of leukemia cells differed from the normal isozymes in electrophoretic. mobility. A single variant was detected in one case of untreated leukemia; a similar component and three additional ones were seen in leukemia treated with 6-mercaptopurine.

Entities:  

Mesh:

Substances:

Year:  1965        PMID: 5213700     DOI: 10.1126/science.150.3692.58

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  3 in total

1.  Cytochemistry and ultrastructure of pathologic granulation in myelogenous leukemia.

Authors:  F Schmalzl; D Huhn; H Asamer; R Rindler; H Braunsteiner
Journal:  Blut       Date:  1973-10

2.  Soluble proteins from human leukocyte granules. I. Esterase activity of cationic proteins.

Authors:  R Rindler; H Braunsteiner
Journal:  Blut       Date:  1973-07

3.  Neutrophil alkaline phosphatase in pregnancy.

Authors:  R W Beal; W M Read; P A Turvey
Journal:  J Clin Pathol       Date:  1967-09       Impact factor: 3.411

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.