Literature DB >> 5212379

Isoenzymes of lactate dehydrogenase in human gastric mucosa and gastric carcinoma tissue.

P E Baume, J E Builder, B H Fenton, L G Irving, D W Piper.   

Abstract

Lactate dehydrogenase (LDH) isoenzymes were demonstrated electrophoretically in human fundic and pyloric gastric mucosae and in gastric carcinoma tissue. Fundic gastric mucosa consistently displayed a pattern with predominance of LD1, LD2, and LD3. Pyloric gastric mucosa and cancer tissue consistently had identical patterns with a predominance of LD2, LD3, and LD4, differing significantly from the LDH isoenzyme pattern of fundic mucosa. The LDH isoenzyme pattern characteristic of fundic mucosa extended very close to the histological junction between body and pyloric gastric mucosa and was not affected by the presence of gastritis in the stomach. These results serve to demonstrate yet another difference between mucosa from the acid-secreting and the pyloric areas of the human stomach.

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Year:  1966        PMID: 5212379

Source DB:  PubMed          Journal:  Gastroenterology        ISSN: 0016-5085            Impact factor:   22.682


  3 in total

1.  Lactate dehydrogenase isoenzyme patterns in isolated cells of pig gastric mucosa.

Authors:  B G Timms; B Prochazka-Perthen
Journal:  Histochem J       Date:  1975-09

2.  [Studies on the pattern and distribution of enzymes in the nucous membrane of the gastrointestinal tract. 3. Electrophoretic characterization of enzymes of the mucous membrane of the stomach, small intestine, and rectum occurring in multiple forms and comparative serum analyses].

Authors:  U E Klein; H C Drube; H T Hansen; H Mielke
Journal:  Klin Wochenschr       Date:  1967-03-01

3.  Supernumerary fractions of lactate dehydrogenase in two malignant gliomas.

Authors:  M Buckell; G K Barnes
Journal:  Br J Cancer       Date:  1968-06       Impact factor: 7.640

  3 in total

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