| Literature DB >> 5212379 |
P E Baume, J E Builder, B H Fenton, L G Irving, D W Piper.
Abstract
Lactate dehydrogenase (LDH) isoenzymes were demonstrated electrophoretically in human fundic and pyloric gastric mucosae and in gastric carcinoma tissue. Fundic gastric mucosa consistently displayed a pattern with predominance of LD1, LD2, and LD3. Pyloric gastric mucosa and cancer tissue consistently had identical patterns with a predominance of LD2, LD3, and LD4, differing significantly from the LDH isoenzyme pattern of fundic mucosa. The LDH isoenzyme pattern characteristic of fundic mucosa extended very close to the histological junction between body and pyloric gastric mucosa and was not affected by the presence of gastritis in the stomach. These results serve to demonstrate yet another difference between mucosa from the acid-secreting and the pyloric areas of the human stomach.Entities:
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Year: 1966 PMID: 5212379
Source DB: PubMed Journal: Gastroenterology ISSN: 0016-5085 Impact factor: 22.682