Literature DB >> 521127

Antispasmodic activity of the tertiary base of Daucus carota, Linn. seeds.

S S Gambhir, S P Sen, A K Sanyal, P K Das.   

Abstract

A nitrogen containing base responding to Mayer's test and Dragendorff's reagent for tertiary bases has been isolated from the seeds of Daucus carota Linn. The effects of the base as its bromide have been studied on smooth muscles of ileum, uterus, blood vessels and trachea of different species of animals. The tertiary base has been found to have papaverine like nonspecific smooth muscle relaxant and spasmolytic activity, but its activity was found to be about one-tenth of that of papaverine.

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Year:  1979        PMID: 521127

Source DB:  PubMed          Journal:  Indian J Physiol Pharmacol        ISSN: 0019-5499


  2 in total

Review 1.  Natural Antispasmodics: Source, Stereochemical Configuration, and Biological Activity.

Authors:  Edith Fabiola Martínez-Pérez; Zaida N Juárez; Luis R Hernández; Horacio Bach
Journal:  Biomed Res Int       Date:  2018-10-08       Impact factor: 3.411

2.  Carrot (Daucus carota L.): Nephroprotective against gentamicin-induced nephrotoxicity in rats.

Authors:  Vamsi Sodimbaku; Latha Pujari; Raviteja Mullangi; Saisudheer Marri
Journal:  Indian J Pharmacol       Date:  2016 Mar-Apr       Impact factor: 1.200

  2 in total

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