Literature DB >> 520454

The importance of the terminal hemi-acetal group for the ionophoric properties of nigericin.

L David, M Chapel, J Gandreuil, G Jeminet, R Durand.   

Abstract

Opening of the terminal hemi-acetal in dihydronigericin drastically reduces the ionophoric properties of nigericin and dehydroxymethylnigericin with 6 intact heterocycles. This is shown by 2 complementary methods, first with a liquid membrane electrode system, secondly by testing their ionophoric activities in rat liver mitochondria.

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Year:  1979        PMID: 520454     DOI: 10.1007/BF01953193

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  6 in total

1.  Effects of grisorixin on glutamate transport and oxidation in rat liver mitochondria. Relationships between transport and oxidation.

Authors:  R Debise; Y Briand; R Durand; P Gachon; G Jeminet
Journal:  Biochimie       Date:  1977       Impact factor: 4.079

2.  The influence of pH on the conductance of lipid bimolecular membranes in relation to the alkaline ion transport induced by carboxylic carriers grisorixin, alborixin and monensin.

Authors:  R Sandeaux; P Seta; G Jeminet; M Alleaume; C Gavach
Journal:  Biochim Biophys Acta       Date:  1978-08-17

Review 3.  Polyether antibiotics: versatile carboxylic acid ionophores produced by Streptomyces.

Authors:  J W Westley
Journal:  Adv Appl Microbiol       Date:  1977       Impact factor: 5.086

4.  The crystal structure of the potassium salt of nigericin.

Authors:  A J Geddes; B Sheldrick; W T Stevenson; L K Steinrauf
Journal:  Biochem Biophys Res Commun       Date:  1974-10-23       Impact factor: 3.575

5.  The structure of nigericin.

Authors:  L K Steinrauf; M Pinkerton; J W Chamberlin
Journal:  Biochem Biophys Res Commun       Date:  1968-10-10       Impact factor: 3.575

6.  [Alkali-cation specificity and carrier qualities of the antibiotics nigericin and monensin].

Authors:  W K Lutz; H K Wipf; W Simon
Journal:  Helv Chim Acta       Date:  1970       Impact factor: 2.164

  6 in total

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