Literature DB >> 520358

Absorbed dose estimation of some 99mTc-hepatobiliary agents.

C Koutoulidis, E Chiotellis, C Lymberis.   

Abstract

The absorbed dose estimates of several organs after administration in humans of six new hepatobiliary agents (five 99mTc-Pyridoxal amino acid complexes and the 99mTc-HIDA) are presented in comparison with 131I-Rose-Bengal. The results indicated that the radiation doses absorbed by the total body and gonads as well as by the critical organ (upper part of the large intestine) are significantly lower than those of Rose Bengal. Therefore, the new 99mTc-agents can be safely applied to humans.

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Year:  1979        PMID： 520358     DOI： 10.1007/BF00300842

Source DB:  PubMed          Journal:  Eur J Nucl Med        ISSN： 0340-6997


  12 in total

1.  MIRD/Dose Estimate Repart No. 7. Summary of current radiation dose estimates to humans from 123I, 124I, 126I, 130I, and 131I as sodium rose bengal.

Authors: 
Journal:  J Nucl Med       Date:  1975-12       Impact factor: 10.057

2.  Technetium 99m-pyridoxylideneglutamate: a new hepatobiliary radiopharmaceutical. I. Experimental aspects.

Authors:  R J Baker; J C Bellen; P M Ronai
Journal:  J Nucl Med       Date:  1975-08       Impact factor: 10.057

3.  Preparation of Tc-99m labeled pyridoxal-amino acid complexes and their evaluation.

Authors:  E Chiotellis
Journal:  Int J Nucl Med Biol       Date:  1977-01

4.  Technetium-99m biliary scanning agents based on pyridoxal: effect of the amino acid component on labelling and biological distribution.

Authors:  R J Baker; J C Bellen
Journal:  Int J Nucl Med Biol       Date:  1977-01

Review 5.  A review of the physiology of the gastrointestinal tract in relation to radiation doses from radioactive materials.

Authors:  I S Eve
Journal:  Health Phys       Date:  1966-02       Impact factor: 1.316

6.  Estimates of absorbed fractions for monoenergetic photon sources uniformly distributed in various organs of a heterogeneous phantom.

Authors:  W S Snyder; H L Fisher; M R Ford; G G Warner
Journal:  J Nucl Med       Date:  1969-08       Impact factor: 10.057

7.  Absorbed fractions for small volumes containing photon-emitting radioactivity.

Authors:  W H Ellett; R M Humes
Journal:  J Nucl Med       Date:  1971-03       Impact factor: 10.057

8.  99mTc-pyridoxylidene glutamate, a gall bladder imaging agent: chemistry of preparation and comparative animal studies with 131I-Rose Bengal.

Authors:  E Chiotellis
Journal:  Int J Nucl Med Biol       Date:  1977-01

9.  99MTc-HIDA, a gallbladder imaging agent: experimental aspects.

Authors:  E Chiotellis; C Sawas-Dimopoulou; C Koutoulidis; M Constantinides
Journal:  Eur J Nucl Med       Date:  1978

10.  Development of new radiopharmaceuticals based on N-substitution of iminodiacetic acid.

Authors:  M D Loberg; M Cooper; E Harvey; P Callery; W Faith
Journal:  J Nucl Med       Date:  1976-07       Impact factor: 10.057
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