Literature DB >> 520347

Quality control of colloid and particulate 99mTc-labeled radiopharmaceuticals.

E P Belkas, S Archimandritis.   

Abstract

A procedure for the radiochemical purity control of colloid and particulate 99mTc-labeled radiopharmaceuticals is described. The proposed technique is based on the use of two chromatograms, using in both, 15% H3PO4 as solvent and impregnated glass fiber media (Gelman ITLC type SG) as stationary phase. A pretreatment of the radiopharmaceutical with 6 N NaOH is involved prior to one chromatographic run. The procedure is fast and the different species (free pertechnetate, 99mTc-Sn-colloid and labeled 99mTc) in a 99mTc-labeled radiopharmaceutical can be determined accurately and with reliability.

Entities:  

Mesh：

Substances：

Year:  1979        PMID： 520347     DOI： 10.1007/BF00263307

Source DB:  PubMed          Journal:  Eur J Nucl Med        ISSN： 0340-6997


  4 in total

1.  Rapid determination of oxidation state of unbound 99mTc and labeling yield in 99mTc-labeled radiopharmaceuticals.

Authors:  L G Colombetti; S Moerlien; G C Patel; S M Pinsky
Journal:  J Nucl Med       Date:  1976-09       Impact factor: 10.057

2.  Chromatographic quality control of 99mTc-labeled compounds.

Authors:  M W Billinghurst
Journal:  J Nucl Med       Date:  1973-11       Impact factor: 10.057

3.  A possible artifact in gel chromatography of some 99m Tc-chelates.

Authors:  P E Valk; C A Dilts; J McRae
Journal:  J Nucl Med       Date:  1973-04       Impact factor: 10.057

4.  Analytical pitfalls with 99m Tc-labeled compounds.

Authors:  W C Eckelman; P Richards
Journal:  J Nucl Med       Date:  1972-03       Impact factor: 10.057
  4 in total
  1 in total

1.  A single-strip mini-paper chromatographic method for rapid purity-control of 99mTc-labeled radiopharmaceuticals.

Authors:  S Sanada; A Ando; I Ando; T Hiraki; K Hisada
Journal:  Eur J Nucl Med       Date:  1986
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.