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Literature DB >> 520102

The SGOT/SGPT ratio--an indicator of alcoholic liver disease.

Abstract

The SGOT/SGPT ratio is significantly elevated in patients with alcoholic hepatitis and cirrhosis (2.85 +/- 0.2) compared with patients with postnecrotic cirrhosis (1.74 +/- 0.2), chronic hepatitis (1.3 +/- 0.17), obstructive jaundice (0.81 +/- 0.06) and viral hepatitis (0.74 +/- 0.07). An SGOT/SGPT ratio greater than 2 is highly suggestive of alcoholic hepatitis and cirrhosis. It occurs in 70% of these patients compared with 26% of patients with postnecrotic cirrhosis, 8% with chronic hepatitis, 4% with viral hepatitis and none with obstructive jaundice.

Entities: Disease Species

Mesh：

Substances：

Year: 1979 PMID： 520102 DOI： 10.1007/BF01324898

Source DB: PubMed Journal: Dig Dis Sci ISSN： 0163-2116 Impact factor: 3.199

8 in total

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Authors: F De Ritis; M Coltorti; G Giusti
Journal: Lancet Date: 1972-03-25 Impact factor: 79.321

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Authors: U Harinasuta; H J Zimmerman
Journal: Gastroenterology Date: 1971-06 Impact factor: 22.682

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Authors: J De Groote; V J Desmet; P Gedigk; G Korb; H Popper; H Poulsen; P J Scheuer; M Schmid; H Thaler; E Uehlinger
Journal: Lancet Date: 1968-09-14 Impact factor: 79.321

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Authors: H J Zimmerman
Journal: Med Clin North Am Date: 1968-11 Impact factor: 5.456

Review 6. The transaminase tests in liver disease.

Authors: R J Clermont; T C Chalmers
Journal: Medicine (Baltimore) Date: 1967-03 Impact factor: 1.889

Review 7. Steatonecrosis--Mallory body type.

Authors: U Harinasuta; B Chomet; K Ishak; H J Zimmerman
Journal: Medicine (Baltimore) Date: 1967-03 Impact factor: 1.889

8. Liver function.

Authors: M D Burke
Journal: Hum Pathol Date: 1975-05 Impact factor: 3.466

8 in total

83 in total

10. Retrospective study of the clinical profile and prognostic indicators in patients of alcoholic liver disease admitted to a tertiary care teaching hospital in Western Nepal.

Authors: Om K Pathak; Raju Paudel; Om B Panta; Hom P Pant; Bishnu R Giri; Baikuntha Adhikari
Journal: Saudi J Gastroenterol Date: 2009 Jul-Sep Impact factor: 2.485

The SGOT/SGPT ratio--an indicator of alcoholic liver disease.

1. Postnecrotic cirrhosis: morphology, etiology and pathogenesis.

2. Serum-transaminase activities in liver disease.

3. Alcoholic steatonecrosis. I. Relationship between severity of hepatic disease and presence of Mallory bodies in the liver.

4. A classification of chronic hepatitis.

5. The differential diagnosis of jaundice.

Review 6. The transaminase tests in liver disease.

Review 7. Steatonecrosis--Mallory body type.

8. Liver function.

1. Various S-GOT/S-GPT ratios in nonviral liver disorders and related physical conditions and life-style.

Review 2. Evaluation of abnormal liver function tests.

Review 3. Liver enzyme alteration: a guide for clinicians.

4. Utility of 'liver function tests' in alcoholic patients.

5. Assessment of abstract reasoning abilities in alcohol-dependent subjects: an fMRI study.

Review 6. Clinical significance in alcoholic patients of commonly encountered laboratory test results.

7. A review on laboratory liver function tests.

8. Quantitative evaluation of liver function with MRI Using Gd-EOB-DTPA.

9. Episodic memory in detoxified alcoholics: contribution of grey matter microstructure alteration.

10. Retrospective study of the clinical profile and prognostic indicators in patients of alcoholic liver disease admitted to a tertiary care teaching hospital in Western Nepal.