Literature DB >> 518200

Methotrexate and fertility in men.

A El-Beheiry, E El-Mansy, N Kamel, N Salama.   

Abstract

The possible deleterious effects of folic acid antagonist methotrexate on the fertility potential have been investigated in 26 male psoriatic patients. Examination for semen, testicular histology, and spermatogenic function using radioactive phosphorus revealed that methotrexate had no unfavorable effect on male fertility. A long follow up of the patients and their offspring is needed to exclude the possible teratogenic effect of the drug.

Entities:  

Mesh：

Substances：

Year:  1979        PMID： 518200     DOI： 10.3109/01485017908985067

Source DB:  PubMed          Journal:  Arch Androl        ISSN： 0148-5016


  10 in total

Review 1.  Behçet's syndrome in pregnancy.

Authors:  Marcus Martineau; Dorian O Haskard; Catherine Nelson-Piercy
Journal:  Obstet Med       Date:  2010-03-04

Review 2.  Infertility in men with inflammatory bowel disease.

Authors:  Takeshi Shin; Hiroshi Okada
Journal:  World J Gastrointest Pharmacol Ther       Date:  2016-08-06

Review 3.  Sexual and reproductive health in rheumatic disease.

Authors:  Monika Østensen
Journal:  Nat Rev Rheumatol       Date:  2017-07-06       Impact factor: 20.543

Review 4.  Inflammatory bowel diseases and human reproduction: a comprehensive evidence-based review.

Authors:  Stefano Palomba; Giuliana Sereni; Angela Falbo; Marina Beltrami; Silvia Lombardini; Maria Chiara Boni; Giovanni Fornaciari; Romano Sassatelli; Giovanni Battista La Sala
Journal:  World J Gastroenterol       Date:  2014-06-21       Impact factor: 5.742

Review 5.  Safety and efficacy of immunomodulators and biologics during pregnancy and lactation for the treatment of inflammatory bowel disease.

Authors:  Sumona Saha; Arnold Wald
Journal:  Expert Opin Drug Saf       Date:  2012-09-06       Impact factor: 4.250

Review 6.  Pregnancy and medications in inflammatory bowel disease.

Authors:  Rena H Cao; Michael C Grimm
Journal:  Obstet Med       Date:  2020-05-11

Review 7.  Sexual Dysfunction and Fertility Problems in Men with Inflammatory Bowel Disease.

Authors:  Yong Eun Park; Tae Oh Kim
Journal:  World J Mens Health       Date:  2019-03-22       Impact factor: 5.400

8.  Attenuation of Methotrexate-Induced Embryotoxicity and Oxidative Stress by Ethyl Pyruvate.

Authors:  Gholamreza Najafi; Elham Atashfaraz; Farah Farokhi
Journal:  Int J Fertil Steril       Date:  2016-06-01

9.  The effect of paternal exposure to immunosuppressive drugs on sexual function, reproductive hormones, fertility, pregnancy and offspring outcomes: a systematic review.

Authors:  L F Perez-Garcia; R J E M Dolhain; S Vorstenbosch; W Bramer; E van Puijenbroek; J M W Hazes; B Te Winkel
Journal:  Hum Reprod Update       Date:  2020-11-01       Impact factor: 15.610

10.  Acute anejaculation, hypogonadism, and fertility preservation in the setting of neurosarcoidosis: case report and literature review.

Authors:  Benjamin Yu; Anne L Darves-Bornoz; Robert E Brannigan; Joshua A Halpern
Journal:  F S Rep       Date:  2020-10-08
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.