Literature DB >> 516740

[Preliminary findings with oral whooping cough vaccination in young infants (author's transl)].

H Maurer, K H Höfler, W Hilbe, E G Huber.   

Abstract

A preliminary report is presented on oral vaccination against whooping cough. 23 babies younger than, and 2 older than nine weeks and 12 newborn infants were vaccinated orally. No side effects were observed. Serum antibody titres did not increase markedly, but no child was seronegative after vaccination. An evident antibody titre rise to a higher level than in serum was found in the saliva. These results point toward an adequate local immunity. At present a definite statement about the efficacy of this oral vaccination is difficult to make. Further investigations are necessary.

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Year:  1979        PMID: 516740

Source DB:  PubMed          Journal:  Wien Klin Wochenschr        ISSN: 0043-5325            Impact factor:   1.704


  4 in total

1.  Pertussis: epidemiology and control.

Authors:  A S Muller; J Leeuwenburg; D S Pratt
Journal:  Bull World Health Organ       Date:  1986       Impact factor: 9.408

2.  Rabbit nasopharyngeal colonization by Bordetella pertussis: the effects of immunization on clearance and on serum and nasal antibody levels.

Authors:  L A Ashworth; R B Fitzgeorge; L I Irons; C P Morgan; A Robinson
Journal:  J Hyg (Lond)       Date:  1982-06

Review 3.  The Role of Mucosal Immunity in Pertussis.

Authors:  Luis Solans; Camille Locht
Journal:  Front Immunol       Date:  2019-01-14       Impact factor: 7.561

4.  Mucosal Immunization with DTaP Confers Protection against Bordetella pertussis Infection and Cough in Sprague-Dawley Rats.

Authors:  Jesse M Hall; Graham J Bitzer; Megan A DeJong; Jason Kang; Ting Y Wong; M Allison Wolf; Justin R Bevere; Mariette Barbier; F Heath Damron
Journal:  Infect Immun       Date:  2021-09-13       Impact factor: 3.441

  4 in total

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