Literature DB >> 51664

Treatment of superficial thrombophlebitis: a randomized, bouble-blind trial of heparinoid cream.

P P Mehta, S Sagar, V V Kakkar.   

Abstract

In a prospective, double-blind, randomized trial the efficacy of a heparinoid in ointment form was assessed in treating superficial thrombophlebitis developing after continuous intravenous infusion. One hundred surgical patients were studied, and clinical examination and the iodine-125-labelled fibrinogen test used to assess the results. The mean time required for the relief of local symptoms and signs and the rate of local decline in radioactivity differed significantly between patients receiving the heparinoid cream and those recieving the placebo.

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Year:  1975        PMID: 51664      PMCID: PMC1674425          DOI: 10.1136/bmj.3.5984.614

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  12 in total

1.  Venous thrombosis during dextrose infusion.

Authors:  D W VERE; C H SYKES; P ARMITAGE
Journal:  Lancet       Date:  1960-09-17       Impact factor: 79.321

2.  [On therapy of inflammatory infiltrate, furuncle etc., with hirudoid].

Authors:  G SCHMIDT
Journal:  Hippokrates       Date:  1960-10-31

3.  [Heparin tolerance test following hirudoid administration].

Authors:  O BRUNNER
Journal:  Gynaecologia       Date:  1954-07

4.  [Hirudoid in the therapy of thrombotic processes in pregnancy and in puerperium].

Authors:  C DIECKMANN
Journal:  Med Klin       Date:  1951-07-20

5.  [The percutaneous resportion of an S35-labelled mucopolysaccharide polysulfuric acid ester].

Authors:  K Buchtela; H Häckel; H Hackl
Journal:  Arzneimittelforschung       Date:  1967-05

6.  125-I-labelled fibrinogen test adapted for routine screening for deep-vein thrombosis.

Authors:  V V Kakkar; A N Nicolaides; J T Renney; J R Friend; M B Clarke
Journal:  Lancet       Date:  1970-03-14       Impact factor: 79.321

7.  [Prevention and treatment of infusion thrombophlebitis with an organo-heparinoid ointment].

Authors:  J Lipecz; K Bihler
Journal:  Med Welt       Date:  1969-07-26

8.  [Hirudoid ointment used prophylactically against infusion thrombophlebitis. A clinical double blind study with bilateral infusions].

Authors:  J Hästbacka; T Tammisto
Journal:  Nord Med       Date:  1967-04-06

9.  [Experimental investigations on the efffectivity of percutaneous therapy in superficial post-traumatic and post-thrombotic conditions].

Authors:  H Tronnier; G Economou; U M Hebert
Journal:  Med Welt       Date:  1967-12-30

10.  Thrombophlebitis-inhibiting effect of percutaneously applied heparinoid ointment during intravenous infusion. Experimental study.

Authors:  P Rantakallio; K Juntunen; O Kauste
Journal:  Ann Paediatr Fenn       Date:  1965
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  4 in total

1.  A topical heparinoid-containing product improves epidermal permeability barrier homeostasis in mice.

Authors:  Ye Yao; Pan Guo; Xiaoyue Feng; Chunping Shen; Junkai Huang; Jiechen Zhang; Peter M Elias; Lizhi Hu; Mao-Qiang Man
Journal:  Exp Dermatol       Date:  2019-07-04       Impact factor: 3.960

Review 2.  Topically applied heparins for the treatment of vascular disorders : a comprehensive review.

Authors:  Cesare Vecchio; Anna Frisinghelli
Journal:  Clin Drug Investig       Date:  2008       Impact factor: 2.859

Review 3.  Treatment for superficial infusion thrombophlebitis of the upper extremity.

Authors:  Marcello Di Nisio; Frank Peinemann; Ettore Porreca; Anne W S Rutjes
Journal:  Cochrane Database Syst Rev       Date:  2015-11-20

Review 4.  Treatment for superficial thrombophlebitis of the leg.

Authors:  Marcello Di Nisio; Iris M Wichers; Saskia Middeldorp
Journal:  Cochrane Database Syst Rev       Date:  2018-02-25
  4 in total

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