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Literature DB >> 5158911

The uptake and efflux of glycine from rat cerebral-cortex slices.

P Joanny, E Barbosa, H Hillman, J Corriol.

Abstract

The kinetics of the influx and efflux of radioactive l-glycine was studied in slices of rat cerebral cortex. The influx showed saturation kinetics and was inhibited by l-alanine. Influx was dependent on the presence of Na(+) ions and a metabolizable substrate. The efflux of glycine was accelerated by alanine. It was concluded that carrier-mediated facilitated diffusion was the mechanism of glycine uptake by, and efflux from, cerebral slices.

Entities: Chemical Species

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Year: 1971 PMID： 5158911 PMCID： PMC1178048 DOI： 10.1042/bj1250255

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

21 in total

1. Amino acid transport in brain cortex slices. I. The relation between energy production and the glucose-dependent transport of glycine.

Authors: P N ABADOM; P G SCHOLEFIELD
Journal: Can J Biochem Physiol Date: 1962-11

2. FREE AMINO ACIDS AND RELATED COMPOUNDS IN DOG BRAIN: POST-MORTEM AND ANOXIC CHANGES, EFFECTS OF AMMONIUM CHLORIDE INFUSION, AND LEVELS DURING SEIZURES INDUCED BY PICROTOXIN AND BY PENTYLENETETRAZOL.

Authors: J K TEWS; S H CARTER; P D ROA; W E STONE
Journal: J Neurochem Date: 1963-09 Impact factor: 5.372

3. SUBSTRATES AND THE POTASSIUM AND SODIUM LEVELS OF GUINEA PIG: CEREBRAL CORTEX SLICES IN VITRO: EFFECTS OF APPLICATION OF ELECTRICAL PULSES, OF INHIBITORS AND OF ANOXIA.

Authors: P JOANNY; H H HILLMAN
Journal: J Neurochem Date: 1963-09 Impact factor: 5.372

7. Role of Na+ and K+ on sugar (2-deoxyglucose) and amino acid (alpha-aminoisobutyric acid) transport in striated muscle.

Authors: D M Kipnis; J E Parrish
Journal: Fed Proc Date: 1965 Sep-Oct

The uptake and efflux of glycine from rat cerebral-cortex slices.

1. Amino acid transport in brain cortex slices. I. The relation between energy production and the glucose-dependent transport of glycine.

2. FREE AMINO ACIDS AND RELATED COMPOUNDS IN DOG BRAIN: POST-MORTEM AND ANOXIC CHANGES, EFFECTS OF AMMONIUM CHLORIDE INFUSION, AND LEVELS DURING SEIZURES INDUCED BY PICROTOXIN AND BY PENTYLENETETRAZOL.

3. SUBSTRATES AND THE POTASSIUM AND SODIUM LEVELS OF GUINEA PIG: CEREBRAL CORTEX SLICES IN VITRO: EFFECTS OF APPLICATION OF ELECTRICAL PULSES, OF INHIBITORS AND OF ANOXIA.

4. L-cystathionine in human brain.

5. Studies on the free amino acids and related compounds in the tissues of the cat.

6. The effect of arsenate on aerobic phosphorylation.

7. Role of Na+ and K+ on sugar (2-deoxyglucose) and amino acid (alpha-aminoisobutyric acid) transport in striated muscle.

8. Amino acid transport in bone. Evidence for separate transport systems for neutral amino and imino acids.

9. The role of Na+ ions in the transport of alpha-aminoisobutyric acid and other amino acids into the lens.

10. Uptake of monosaccharides by guinea-pig cerebral-cortex slices.

1. Transport of tryptophan and tyrosine in rat brain slices in the presence of lithium.

2. The uptake and efflux of L-phenylalanine and L-tyrosine from rat brain cerebral cortex slices.