Literature DB >> 5157135

Secretin and cholecystokin-pancreozymin in combination in the inhibition of gastric acid secretion.

B S Bedi, H T Debas, A E Wasunna, B F Buxton, I E Gillespie.   

Abstract

Both secretin, and the single substance which possesses both cholecystokinin and pancreozymin activity, have been shown to inhibit gastric acid secretory responses. Since potentiation may occur between pairs of stimulants of gastric secretion, the effects of combining secretin and cholecystokinin/pancreozymin have been studied in Heidenhain pouches stimulated by continuous intravenous pentagastrin. Evidence suggesting potentiation between these two inhibitor agents is presented.

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Year:  1971        PMID: 5157135      PMCID: PMC1411986          DOI: 10.1136/gut.12.12.968

Source DB:  PubMed          Journal:  Gut        ISSN: 0017-5749            Impact factor:   23.059


  15 in total

1.  Gastrin, cholecystokinin, and secretin act on one receptor.

Authors:  M I Grossman
Journal:  Lancet       Date:  1970-05-23       Impact factor: 79.321

2.  Effect of secretin on acid and pepsin secretion in cat and dog.

Authors:  G F Stening; L R Johnson; M I Grossman
Journal:  Gastroenterology       Date:  1969-03       Impact factor: 22.682

3.  Characteristics of inhibition of gastric secretion by secretin.

Authors:  L R Johnson; M I Grossman
Journal:  Am J Physiol       Date:  1969-11

4.  Secretin: the enterogastrone released by acid in the duodenum.

Authors:  L R Johnson; M I Grossman
Journal:  Am J Physiol       Date:  1968-10

5.  Observations on the effect of diversion of acid from the duodenum in response to gastrin and histamine.

Authors:  A R Cooke
Journal:  Gastroenterology       Date:  1968-08       Impact factor: 22.682

6.  The isolation and chemistry of secretin and cholecystokinin.

Authors:  J E Jorpes
Journal:  Gastroenterology       Date:  1968-08       Impact factor: 22.682

7.  Effect of bile salts on antral gastrin release.

Authors:  B S Bedi; H T Debas; G Gillespie; I E Gillespie
Journal:  Gastroenterology       Date:  1971-02       Impact factor: 22.682

8.  Effect of cholecystokinin and caerulein on gastrin- and histamine-evoked gastric secretion.

Authors:  G F Stening; L R Johnson; M L Grossman
Journal:  Gastroenterology       Date:  1969-07       Impact factor: 22.682

9.  Measurement of pancreatic exocrine function in health and disease.

Authors:  K G Wormsley
Journal:  Br J Surg       Date:  1969-09       Impact factor: 6.939

10.  Effect of perfusion of intestinal loops with acid, fat, or dextrose on gastric secretion.

Authors:  S Konturek; M I Grossman
Journal:  Gastroenterology       Date:  1965-11       Impact factor: 22.682

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