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Literature DB >> 5157129

Mechanism of fat malabsorption in rats infected with Nippostrongylus brasiliensis.

N D Gallagher, M R Playoust, L E Symons.

Abstract

Long-chain fatty acid absorption in rats with a jejunal lesion similar to that which is found in adult coeliac disease has been studied. Neither changes in the solubility of the fatty acid in the intestinal lumen nor histological abnormalities of the villous epithelium accounted for the malabsorptive state. Evidence was obtained from studies in vivo of a disturbance in the intramucosal esterification of long-chain fatty acid. Assay of the activity of the microsomal enzymes responsible for the conversion of fatty acid to triglyceride revealed that this pathway was defective in the parasitized animals.

Entities: Chemical Disease Species

Mesh：

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Year: 1971 PMID： 5157129 PMCID： PMC1412000 DOI： 10.1136/gut.12.12.1007

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

12 in total

Review 1. INTESTINAL ABSORPTION OF FATS.

Authors: J R SENIOR
Journal: J Lipid Res Date: 1964-10 Impact factor: 5.922

2. EFFECT OF INTESTINAL RESECTION ON BILE SALT ABSORPTION IN DOGS.

Authors: M R PLAYOUST; L LACK; I M WEINER
Journal: Am J Physiol Date: 1965-02

3. KINETICS OF THE EPITHELIAL CELLS, AND MORPHOLOGY OF VILLI AND CRYPTS IN THE JEJUNUM OF THE RAT INFECTED BY THE NEMATODE NIPPOSTRONGYLUS BRASILIENSIS.

Authors: L E SYMONS
Journal: Gastroenterology Date: 1965-08 Impact factor: 22.682

4. Pathology, absorption, transport, and activity of digestive enzymes in rat jejunum parasitized by the nematode Nippostrongylus brasiliensis.

Authors: L E SYMONS; D FAIRBAIRN
Journal: Fed Proc Date: 1962 Nov-Dec

9. Three-dimensional structure of the rat small intestinal mucoas related to mucosal dynamics. 3. Mucosal structure and dynamics in the rat infested with the nematode Nippostrongylus brasiliensis.

Authors: C A Loehry; B Creamer
Journal: Gut Date: 1969-02 Impact factor: 23.059

10. Cell turnover in the rat small intestinal mucosa: an appraisal of cell loss. II. Cell loss in rats with an abnormal mucosa.

Authors: C A Loehry; D N Croft; A K Singh; B Creamer
Journal: Gut Date: 1969-01 Impact factor: 23.059

1 in total

1. Mechanisms of lipid loss from the small intestinal mucosa.

Authors: R Waldram
Journal: Gut Date: 1975-02 Impact factor: 23.059

1 in total

Mechanism of fat malabsorption in rats infected with Nippostrongylus brasiliensis.

Review 1. INTESTINAL ABSORPTION OF FATS.

2. EFFECT OF INTESTINAL RESECTION ON BILE SALT ABSORPTION IN DOGS.

3. KINETICS OF THE EPITHELIAL CELLS, AND MORPHOLOGY OF VILLI AND CRYPTS IN THE JEJUNUM OF THE RAT INFECTED BY THE NEMATODE NIPPOSTRONGYLUS BRASILIENSIS.

4. Pathology, absorption, transport, and activity of digestive enzymes in rat jejunum parasitized by the nematode Nippostrongylus brasiliensis.

5. Biochemical pathology of the rat jejunum parasitized by the nematode nippostrongylus brasiliensis.

6. A morphologic and histochemical analysis of the human jejunal epithelium in nontropical sprue.

7. The esterification of palmitate-1-C14 by homogenates of intestinal mucosa.

8. A simple method for the isolation and purification of total lipides from animal tissues.

9. Three-dimensional structure of the rat small intestinal mucoas related to mucosal dynamics. 3. Mucosal structure and dynamics in the rat infested with the nematode Nippostrongylus brasiliensis.

10. Cell turnover in the rat small intestinal mucosa: an appraisal of cell loss. II. Cell loss in rats with an abnormal mucosa.

1. Mechanisms of lipid loss from the small intestinal mucosa.