Literature DB >> 515510

Influence of pyrazole, an inhibitor of alcohol dehydrogenase on the prenatal toxicity of ethanol in the rat.

P K Varma, T V Persaud.   

Abstract

Pyrazole, a potent inhibitor of alcohol dehydrogenase, induced a high incidence of ocular and urinary bladder anomalies in the offspring of rats following treatment on gestational day 9. A single moderate dose of ethanol potentiated the teratogenic action of pyrazole, but alone did not affect embryonic development.

Entities:  

Mesh：

Substances：

Year:  1979        PMID： 515510

Source DB:  PubMed          Journal:  Res Commun Chem Pathol Pharmacol        ISSN： 0034-5164


  2 in total

1.  Construction of vapor chambers used to expose mice to alcohol during the equivalent of all three trimesters of human development.

Authors:  Russell A Morton; Marvin R Diaz; Lauren A Topper; C Fernando Valenzuela
Journal:  J Vis Exp       Date:  2014-07-13       Impact factor: 1.355

Review 2.  Fetal alcohol syndrome: the vulnerability of the developing brain and possible mechanisms of damage.

Authors:  J R West; W J Chen; N J Pantazis
Journal:  Metab Brain Dis       Date:  1994-12       Impact factor: 3.584
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.