Literature DB >> 514264

The highly tumorigenic 3,4-dihydrodiol is a principal metabolite formed from dibenzo[a,h]anthracene by liver enzymes.

M Nordqvist, D R Thakker, W Levin, H Yagi, D E Ryan, P E Thomas, A H Conney, D M Jerina.   

Abstract

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Year:  1979        PMID： 514264

Source DB:  PubMed          Journal:  Mol Pharmacol        ISSN： 0026-895X            Impact factor:   4.436


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  4 in total

1.  Mutagenicity and tumorigenicity of the four enantiopure bay-region 3,4-diol-1,2-epoxide isomers of dibenz[a,h]anthracene.

Authors:  Richard L Chang; Alexander W Wood; Mou Tuan Huang; Jian Guo Xie; Xiao Xing Cui; Kenneth R Reuhl; D R Boyd; Yong Lin; Weichung Joe Shih; Suresh K Balani; Haruhiko Yagi; Donald M Jerina; Allan H Conney
Journal:  Carcinogenesis       Date:  2013-05-13       Impact factor: 4.944

Review 2.  Activation mechanisms to chemical toxicity.

Authors:  D V Parke
Journal:  Arch Toxicol       Date:  1987       Impact factor: 5.153

3.  Metabolic conversion of dibenz[a,h]anthracene (+/-)trans-1,2-dihydrodiol and chrysene (+/-)trans-3,4-dihydrodiol to vicinal dihydrodiol epoxides.

Authors:  M W Chou; P P Fu; S K Yang
Journal:  Proc Natl Acad Sci U S A       Date:  1981-07       Impact factor: 11.205

4.  Stereoselective metabolism of dibenz(a,h)anthracene to trans-dihydrodiols and their activation to bacterial mutagens.

Authors:  K L Platt; M Schollmeier; H Frank; F Oesch
Journal:  Environ Health Perspect       Date:  1990-08       Impact factor: 9.031
  4 in total

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