Literature DB >> 514124

Fatal thioridazine cardiotoxicity.

K R Burgess, R W Jefferis, I F Stevenson.   

Abstract

A case of fatal cardiotoxicity after a deliberate ingestion of 5000 mg thioridazine (Melleril) is reported. The serum thioridazine level is documented for the first time at the time of arrhythmia. Correct treatment of similar cases should often include insertion of a transvenous pacing wire, as the arrhythmias are generally resistant to drug therapy.

Entities:  

Mesh:

Substances:

Year:  1979        PMID: 514124     DOI: 10.5694/j.1326-5377.1979.tb142025.x

Source DB:  PubMed          Journal:  Med J Aust        ISSN: 0025-729X            Impact factor:   7.738


  2 in total

1.  A case of risperidone overdose in early schizophrenia: a review of potential complications.

Authors:  L C Kopala; C Day; B Dillman; D Gardner
Journal:  J Psychiatry Neurosci       Date:  1998-11       Impact factor: 6.186

2.  The biotransformation of thioridazine to thioridazine 5-sulfoxide stereoisomers in phenobarbital induced rats.

Authors:  P W Hale; A Poklis
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1986 Oct-Dec       Impact factor: 2.441

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.