Literature DB >> 5139537

Study of adenine aminohydrolase in the yeast, Schizosaccharomyces pombe.

A Abbondandolo, A Weyer, H Heslot, M Lambert.   

Abstract

Observation of the growth of some adenineless mutants of Schizosaccharomyces pombe on six substituted purine analogs leads to the hypothesis that an enzyme is present which catalyzes the conversion of these analogs into hypoxanthine. The enzyme adenase (adenine aminohydrolase, EC 3.5.4.2) has been found to be active in cell-free extracts of S. pombe. Results are reported which are in agreement with the hypothesis that this enzyme is responsible for the in vivo utilization of 6-chloropurine. This evidence comes mainly from a study of adenine aminohydrolase in two mutants selected for partial inability to grow on 6-chloropurine.

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Year:  1971        PMID： 5139537      PMCID： PMC247174          DOI： 10.1128/jb.108.3.959-963.1971

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  6 in total

1.  REGULATION OF ADENYLATE DEAMINASE BY ADENOSINE TRIPHOSPHATE.

Authors:  B CUNNINGHAM; J M LOWENSTEIN
Journal:  Biochim Biophys Acta       Date:  1965-03-22

2.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

3.  Alkali cation-activated AMP deaminase of erythrocytes: some properties of the membrane-bound enzyme.

Authors:  S N Rao; L Hara; A Askari
Journal:  Biochim Biophys Acta       Date:  1968-03-25

4.  Purine catabolism in Drosophila melanogaster. I. Reactions leading to xanthine dehydrogenase.

Authors:  L D Hodge; E Glassman
Journal:  Biochim Biophys Acta       Date:  1967-12-19

5.  Adenine aminohydrolase. An investigation of specificity.

Authors:  R C Hartenstein; I Fridovich
Journal:  J Biol Chem       Date:  1967-02-25       Impact factor: 5.157

6.  Adenine uptake and pool formation in the fission yeast Schizosaccharomyces pombe.

Authors:  J E Cummins; J M Mitchison
Journal:  Biochim Biophys Acta       Date:  1967-02-07
  6 in total
  3 in total

1.  Adenosine accumulation in Saccharomyces cerevisiae cultured in medium containing low levels of adenine.

Authors:  H M Laten; P J Valentine; C A van Kast
Journal:  J Bacteriol       Date:  1986-06       Impact factor: 3.490

Review 2.  Degradation of purines and pyrimidines by microorganisms.

Authors:  G D Vogels; C Van der Drift
Journal:  Bacteriol Rev       Date:  1976-06

3.  Cytokinin Utilization by Adenine-Requiring Mutants of the Yeast Saccharomyces cerevisiae.

Authors:  C A Van Kast; H M Laten
Journal:  Plant Physiol       Date:  1987-04       Impact factor: 8.340
  3 in total

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