Literature DB >> 512855

Modification of metoclopramide GLC assay: application to human biological specimens.

Y K Tam, J E Axelson, R Ongley.   

Abstract

A modified electron-capture GLC assay for metoclopramide in human biological specimens is reported. This assay involves the incorporation of a back-extraction method to remove endogenous contaminants. Its applicability was demonstrated by studying the time course of metoclopramide in plasma and urine from a human subject. The lowest quantifiable metoclopramide concentration in plasma was 7 ng/ml, provided 0.5 ml of plasma was used.

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Year:  1979        PMID: 512855     DOI: 10.1002/jps.2600681015

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN: 0022-3549            Impact factor:   3.534


  2 in total

Review 1.  Clinical pharmacokinetics of drugs used in the treatment of gastrointestinal diseases (Part II).

Authors:  K Lauritsen; L S Laursen; J Rask-Madsen
Journal:  Clin Pharmacokinet       Date:  1990-08       Impact factor: 6.447

Review 2.  Clinical pharmacokinetics of metoclopramide.

Authors:  D N Bateman
Journal:  Clin Pharmacokinet       Date:  1983 Nov-Dec       Impact factor: 6.447

  2 in total

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