Literature DB >> 511780

4-N-Aminoacylfortimicins E.

P Kurath, D Grampovnik, J Tadanier, J R Martin, R S Egan, R S Stanaszek, M Cirovic, W H Washburn, P Hill, D A Dunnigan, J E Leonard, P Johnson, A W Goldstein.   

Abstract

The conversion of fortimicin E, a minor metabolite from the Micromonospora olivoasterospora fermentation which also produces fortimicin A and fortimicin B, to four 4-N-aminoacylfortimicins E was accomplished. The new 4-N-aminoacylfortimicins E showed only weak antimicrobial activity against several Gram-negative and Gram-positive microorganisms.

Entities:  

Mesh:

Substances:

Year:  1979        PMID: 511780     DOI: 10.7164/antibiotics.32.884

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  1 in total

1.  Compound A49759, the 3-O-demethyl derivative of fortimicin A: in vitro comparison with six other aminoglycoside antibiotics.

Authors:  R N Jones; C Thornsberry; A L Barry; R R Packer; C N Baker; R E Badal
Journal:  Antimicrob Agents Chemother       Date:  1980-11       Impact factor: 5.191

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.