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Literature DB >> 511364

Review of side-effects of aminopenicillins.

Abstract

Side-effects of aminopenicillin therapy are reviewed on the basis of nine comparative studies of ampicillin and bacampicillin, and available literature data from investigations with talampicillin, pivampicillin, bacampicillin and amoxycillin. Diarrhoea is more common with ampicillin than with newer aminopenicillins. Exanthema do not appear more frequently with newer aminopenicillins. The frequency of upper gastrointestinal complaints in association with some of the newer aminopenicillins (amoxycillin, bacampicillin) is not more frequent than with ampicillin. All current evidence speaks in favour of a change from ampicillin to modern aminopenicillins for oral therapy.

Entities: Chemical Disease

Mesh：

Substances：
Ampicillin
Amoxicillin

Year: 1979 PMID： 511364 DOI： 10.1007/bf01659784

Source DB: PubMed Journal: Infection ISSN： 0300-8126 Impact factor: 3.553

21 in total

Review of side-effects of aminopenicillins.

1. A multicentre comparative trial of talampicillin and ampicillin in general practice.

2. [Advantages of a rapidly and well-absorbed oral antibiotic in the treatment of infectious diseases].

3. A comparison of pivampicillin and tetracycline in exacerbations of chronic bronchitis.

4. [Treatment of urinary tract infections using pivampicillin].

5. Antibiotic treatment with pivampicillin chloride in respiratory and urinary tract infections.

6. [Long-term treatment with pivampicillin chloride. A clinical toxicologic study].

7. [Comparative study of therapeutic methods in the treatment of acute salpingitis].

8. Bacampicillin in acute exacerbations of chronic bronchitis--a dose-range study.

9. Twice daily dosage of bacampicillin in chronic bronchitis. A double-blind study.

10. Pharmacological and clinical study of bacampicillin in acute peritonsillitis--a comparison with ampicillin.

Review 1. Studies on aminopenicillin developments. Proceedings of a symposium. Concluding remarks.

Review 2. The aminopenicillins: development and comparative properties.

3. Pharmacokinetics of ampicillin and its prodrugs bacampicillin and pivampicillin in man.

4. Efficacy of penicillin treatment in purulent maxillary sinusitis. A European multicenter trial.