Literature DB >> 5112644

Effect of pancreozymin on rat pancreatic enzyme biosynthesis.

H Reggio, H Cailla-Deckmyn, G Marchis-Mouren.   

Abstract

Pancreatic enzyme secretion in rats anesthesized by pentobarbital was stimulated by intravenous perfusion of the hormone pancreozymin, as indicated by a decreased amylase level in the pancreas and by specific, fine structural changes observed in an electron microscope. Rates of protein synthesis were determined by pulse labeling. Amylase, total protein, and valine were purified from pancreas and counted. Pancreozymin promotes an 8 to 10 times increase in the rate of biosynthesis of pancreatic enzymes, as compared to rats similarly anesthesized but without hormone. This stimulation effect is obtained very rapidly (2 hr) and is not inhibited by actinomycin D. Secretin alone has no effect, whereas pentobarbital is inhibitory.

Entities:  

Mesh：

Substances：

Year:  1971        PMID： 5112644      PMCID： PMC2108282          DOI： 10.1083/jcb.50.2.333

Source DB:  PubMed          Journal:  J Cell Biol        ISSN： 0021-9525            Impact factor:   10.539


  12 in total

1.  A comparison of the respiratory activity and histological changes in isolated pancreatic tissue.

Authors:  R E DAVIES; A A HARPER; I F S MACKAY
Journal:  Am J Physiol       Date:  1949-05

2.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

3.  Protein synthesis in the pancreas of the rat after stimulation of secretion.

Authors:  M F Kramer; C Poort
Journal:  Z Zellforsch Mikrosk Anat       Date:  1968

4.  Effect of intravenous pancreozymin on amino acid incorporation in vitro by pancreatic tissue.

Authors:  P D Webster; M P Tyor
Journal:  Am J Physiol       Date:  1966-07

5.  Inhibition by actinomycin D of valine incorporation into specific proteins of rat pancreas in vivo.

Authors:  G Marchis-Mouren; A Cozzone
Journal:  Biochemistry       Date:  1966-11       Impact factor: 3.162

6.  Studies on the transfer of incomplete polypeptide chains across rat liver microsomal membranes in vitro.

Authors:  C M Redman
Journal:  J Biol Chem       Date:  1967-02-25       Impact factor: 5.157

7.  [Adaptation of the rate of biosynthesis of pancreatic amylase and chymotrypsinogen A to starch-rich or protein-rich diets].

Authors:  J P Reboud; G Marchis-Mouren; L Paséro; A Cozzone; P Desnuelle
Journal:  Biochim Biophys Acta       Date:  1966-04-25

8.  PROTEIN SYNTHESIS, STORAGE, AND DISCHARGE IN THE PANCREATIC EXOCRINE CELL. AN AUTORADIOGRAPHIC STUDY.

Authors:  L G CARO; G E PALADE
Journal:  J Cell Biol       Date:  1964-03       Impact factor: 10.539

9.  FINE STRUCTURAL CHANGES IN RESPONSE TO HORMONAL STIMULATION OF THE PERFUSED CANINE PANCREAS.

Authors:  A ICHIKAWA
Journal:  J Cell Biol       Date:  1965-03       Impact factor: 10.539

10.  A cyto-chemical study on the pancreas of the guinea pig. III. In vivo incorporation of leucine-1-C14 into the proteins of cell fractions.

Authors:  P SIEKEVITZ; G E PALADE
Journal:  J Biophys Biochem Cytol       Date:  1958-09-25
View more
  11 in total

1.  Studies on intracellular transport of secretory proteins in the rat exocrine pancreas. IV. Stimulation by in vivo infusion of caerulein.

Authors:  W Bieger; A Martin-Achard; M Bassler; H F Kern
Journal:  Cell Tissue Res       Date:  1976-01-28       Impact factor: 5.249

2.  [Amino acid level in plasma--expressed as alpha-amino-nitrogen--reaction to stimulation of the exocrine pancreas: approaches to a new pancreatic function test].

Authors:  G Heptner; S Domschke; M U Schneider; S Kolb; W Domschke
Journal:  Klin Wochenschr       Date:  1987-11-02

3.  Time course and cellular site of mitotic activity in the exocrine pancreas of the rat during sustained hormone stimulation.

Authors:  H Lütcke; G A Scheele; H F Kern
Journal:  Cell Tissue Res       Date:  1987-02       Impact factor: 5.249

4.  Amino acid transport in the rat exocrine pancreas. III. Effect of maximal and supramaximal hormonal stimulation in vivo.

Authors:  G Adler; W Bieger; H F Kern
Journal:  Cell Tissue Res       Date:  1978-12-12       Impact factor: 5.249

5.  Caerulein stimulates pancreatic secretory response in conscious newborn rats.

Authors:  M Papp; D A Dreiling; I Dobronyi; G Varga
Journal:  Int J Pancreatol       Date:  1989-03

6.  The effect of feeding on the secretion of pepsin, trypsin and chymotrypsin in the Atlantic salmon,Salmo salar L.

Authors:  S Einarsson; P S Davies; C Talbot
Journal:  Fish Physiol Biochem       Date:  1996-11       Impact factor: 2.794

7.  In-vivo stimulation of rat pancreatic acinar cells by infusion of secretin. I. Changes in enzyme content, pancreatic fine structure and total rate of protein synthesis.

Authors:  U Rausch; P Vasiloudes; K Rüdiger; H F Kern
Journal:  Cell Tissue Res       Date:  1985       Impact factor: 5.249

8.  Creatine phosphate as energy source in the cerulein-stimulated rat pancreas study by 31P nuclear magnetic resonance.

Authors:  S Aired; Y Creach; C Palevody; J Esclassan; E Hollande
Journal:  Int J Pancreatol       Date:  1991-09

9.  Dissociation between pancreatic enzyme secretory and synthetic dose-responses to cholecystokinin in man.

Authors:  E J Boyd; J Dunbar; G Clarke; K G Wormsley
Journal:  Int J Pancreatol       Date:  1986-05

10.  The effects of secretagogues on the incorporation of (2- 3 H)myoinositol into lipid in cytological fractions in the pancreas of the guinea pig in vivo.

Authors:  D Gerber; M Davies; L E Hokin
Journal:  J Cell Biol       Date:  1973-03       Impact factor: 10.539
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.