Literature DB >> 5111564

Dental caries: prospects for prevention.

H W Scherp.   

Abstract

Combined utilization of measures now available or imminent could reduce caries of the crowns of the teeth to the point of negligibility as a public health problem, if public desire were great enough to motivate changes in some of our habits (64). Universal optimum application of fluoride and substitution of starchy foods for sugary ones (or even simply judicious consumption of sugar) would alone do most of the job. Sealing of susceptible occlusal areas with adhesive polymers promises to protect the sites where fluoride evidently cannot be maximally effective. It seems unlikely that any single measure will be found sufficient to control this multifactorial disease. Consequently, we must continue the search for new means to increase the caries resistance of teeth, to reduce the cariogenicity of foodstuffs, and to check the deleterious activities of cariogenic bacteria. Anticaries food additives and antibacterial agents for intraoral use seem to be approaching practicability. Past performance warrants expectation that ongoing fundamental investigations will produce leads for future development and application.

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Year:  1971        PMID: 5111564     DOI: 10.1126/science.173.4003.1199

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  49 in total

1.  Prevention of Streptococcus mutans infection of tooth surfaces by salivary antibody in Irus monkeys (Macaca fascicularis).

Authors:  R T Evans; F G Emmings; R J Genco
Journal:  Infect Immun       Date:  1975-08       Impact factor: 3.441

2.  Biotechnology and ecological studies on the oral cavity.

Authors:  S A Robrish
Journal:  Microb Ecol       Date:  1986-03       Impact factor: 4.552

3.  Properties of Streptococcus mutans grown in a synthetic medium: binding of glucosyltransferase and in vitro adherence, and binding of dextran/glucan and glycoprotein and agglutination.

Authors:  C D Wu-Yuan; S Tai; H D Slade
Journal:  Infect Immun       Date:  1979-03       Impact factor: 3.441

4.  Genetic transformation of Streptococcus mutans.

Authors:  D Perry; H K Kuramitsu
Journal:  Infect Immun       Date:  1981-06       Impact factor: 3.441

5.  Mechanism of adherence of Streptococcus mutans to smooth surfaces. I. Roles of insoluble dextran-levan synthetase enzymes and cell wall polysaccharide antigen in plaque formation.

Authors:  H Mukasa; H D Slade
Journal:  Infect Immun       Date:  1973-10       Impact factor: 3.441

6.  Naturally occurring secretory immunoglobulin A antibodies to Streptococcus mutans in human colostrum and saliva.

Authors:  R R Arnold; J Mestecky; J R McGhee
Journal:  Infect Immun       Date:  1976-08       Impact factor: 3.441

7.  Serological purification of polysaccharide antigens from Streptococcus mutans serotypes a and d: characterization of multiple antigenic determinants.

Authors:  R Linzer; H Mukasa; H D Slade
Journal:  Infect Immun       Date:  1975-10       Impact factor: 3.441

8.  The buccale puzzle: The symbiotic nature of endogenous infections of the oral cavity.

Authors:  John Ruby; Jean Barbeau
Journal:  Can J Infect Dis       Date:  2002-01

9.  Production of extracellular and cell-associated glucosyltransferase activity by Streptococcus mutans during growth on various carbon sources.

Authors:  W M Janda; H K Kuramitsu
Journal:  Infect Immun       Date:  1978-01       Impact factor: 3.441

10.  Effective immunity to dental caries: dose-dependent studies of secretory immunity by oral administration of Streptococcus mutans to rats.

Authors:  S M Michalek; J R McGhee; J L Babb
Journal:  Infect Immun       Date:  1978-01       Impact factor: 3.441

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