Literature DB >> 510506

Effect of human seminal plasma on tumour-associated immunity in prostatic cancer. A preliminary report.

R J Ablin, R A Bhatti, P D Guinan, I M Bush.   

Abstract

Evidence of significant suppression of tumour-associated immunity in patients with prostatic cancer by human seminal plasma (HuSPl) has been observed. Collation of the immunosuppressive property of HuSPl in this and previous studies, together with recent studies demonstrating experimental induction of prostatic cancer by spermatozoa and the relationship of prostatic cancer to sexual activity are suggestive of an etiologic role for SPl in prostatic cancer.

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Year:  1979        PMID： 510506     DOI： 10.1007/bf01962815

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  15 in total

1.  Immunosuppressive activity of human seminal plasma. I. Inhibition of in vitro lymphocyte activation.

Authors:  E M Lord; G F Sensabaugh; D P Stites
Journal:  J Immunol       Date:  1977-05       Impact factor: 5.422

Review 2.  Occult carcinoma of the prostate: an oversight of immune surveillance--a working hypothesis.

Authors:  R F Gittes; D L McCullough
Journal:  J Urol       Date:  1974-08       Impact factor: 7.450

3.  Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

Authors:  A Böyum
Journal:  Scand J Clin Lab Invest Suppl       Date:  1968

4.  Cancer of the prostate. I.

Authors:  J D Fergusson
Journal:  Br Med J       Date:  1970-11-21

5.  On the incidence of carcinoma of the prostate.

Authors:  D J Ashley
Journal:  J Pathol Bacteriol       Date:  1965-07

6.  In vitro studies in reproductive immunology. 1. Suppression of cell-mediated immune response by human spermatozoa and fractions isolated from human seminal plasma.

Authors:  Z H Marcus; J H Freisheim; J L Houk; J H Herman; E V Hess
Journal:  Clin Immunol Immunopathol       Date:  1978-03

7.  Cell-mediated antitumor immunity in breast cancer patients evaluated by antigen-induced leukocyte adherence inhibition in test tubes.

Authors:  N Grosser; D M Thomson
Journal:  Cancer Res       Date:  1975-09       Impact factor: 12.701

8.  On the etiology of cancer of the prostate.

Authors:  R Stein-Werblowky
Journal:  Eur Urol       Date:  1978       Impact factor: 20.096

9.  Leukocyte adherence inhibition and immunoreactivity in prostatic cancer. II. Tissue- and disease-specificity of antitumour cell-mediated immunity.

Authors:  R A Bhatti; R J Ablin; P D Guinan
Journal:  Eur J Cancer       Date:  1979-01       Impact factor: 9.162

10.  Evaluation of cellular immunologic responsiveness in the clinical management of patients with prostatic cancer. III. Inhibition of leucocyte migration.

Authors:  R J Ablin; C Marrow; P D Guinan; G R Bruns; N Sadoughi; T John; I M Bush
Journal:  Urol Int       Date:  1976       Impact factor: 2.089
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  1 in total

1.  Suppression of cytophilic antibody ('arming' factor) in the sera of patients with prostatic cancer by human seminal plasma.

Authors:  R A Bhatti; R J Ablin; S Zamora; E Totonchi; I M Bush; P D Guinan
Journal:  Experientia       Date:  1980-03-15
  1 in total

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