Literature DB >> 510496

DPH-induced macrocytosis in the 14-day rat foetus.

C Petter.   

Abstract

Phenytoin injected in the pregnant rat induces in the 14-day-old foetus macrocytosis of the primitive red blood cells which is sometimes linked with limb haemorrhages. The action of the drug is possibly the result of a blood circulation disturbance.

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Year:  1979        PMID: 510496     DOI: 10.1007/bf01962805

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  14 in total

1.  Teratogenic activity of the antiepileptic drugs phenobarbital, phenytoin, and primidone in mice.

Authors:  F M Sullivan; P R McElhatton
Journal:  Toxicol Appl Pharmacol       Date:  1975-11       Impact factor: 4.219

2.  Foetal red cell macrocytosis induced by pyrimethamine; its teratogenic role.

Authors:  C Petter; J Bourbon
Journal:  Experientia       Date:  1975-03-15

3.  The effect of cortisone on the teratogenic action of acetylsalicylic acid and diphenylhydantoin in the mouse.

Authors:  H Fritz
Journal:  Experientia       Date:  1976-06-15

4.  Neonatal coagulation defect due to anticonvulsant drug treatment in pregnancy.

Authors:  K R Mountain; J Hirsh; A S Gallus
Journal:  Lancet       Date:  1970-02-07       Impact factor: 79.321

5.  Folate deficiency in malnutrition, malabsorption, and during phenytoin treatment diagnosed by determination of serine synthesis in lymphocytes.

Authors:  J Ellegaard; V Esmann
Journal:  Eur J Clin Invest       Date:  1972-08       Impact factor: 4.686

6.  Methotrexate-induced congenital malformations.

Authors:  H R Powell; H Ekert
Journal:  Med J Aust       Date:  1971-11-20       Impact factor: 7.738

7.  Relation of dosage and time of administration of diphenylhydantoin to its teratogenic effect in mice.

Authors:  R D Harbison; B A Becker
Journal:  Teratology       Date:  1969-11

8.  Aminopterin-induced fetal malformation. Survival of infant after attempted abortion.

Authors:  E B Shaw; H L Steinback
Journal:  Am J Dis Child       Date:  1968-04

9.  Simultaneous prevention of blood abnormalities and hereditary congenital amputations in a brachydactylous rabbit stock.

Authors:  C Petter; J Bourbon; J P Maltier; A Jost
Journal:  Teratology       Date:  1977-04

10.  Megaloblastic anaemia in anticonvulsant therapy.

Authors:  M J Meynell
Journal:  Lancet       Date:  1966-02-26       Impact factor: 79.321

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