| Literature DB >> 5103943 |
Abstract
In mice the activation caused by morphine was antagonized by previous treatment with lithium and was potentiated by previous treatment with rubidium. Other antimanic drugs antagonized the morphine activation as well. The effect of rubidium was similar to that of the antidepressant drugs imipramine and pargyline. Rubidium may merit clinical evaluation as an antidepressant agent in man.Entities:
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Year: 1971 PMID: 5103943 DOI: 10.1126/science.172.3990.1355
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728