Literature DB >> 5102476

Lymphocyte stimulation: selective destruction of cells during blastogenic response to transplantation antigens.

S E Salmon, R S Krakauer, W F Whitmore.   

Abstract

The blastogenic response of human lymphoid cells toward any individual's transplantation antigens can be deleted by the addition of tritiated thymidine of high specific activity during the incubation of the lymphoid cells in mixed leukocyte culture. After the immunocompetent clones which responded to histocompatibility antigens had been destroyed, the remaining population still retained its capacity to respond to unrelated antigens, including other transplantation antigens.

Entities:  

Mesh：

Substances：

Year:  1971        PMID： 5102476     DOI： 10.1126/science.172.3982.490

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  8 in total

1.  Human T lymphocytes grown in T-cell growth factor: functional attributes in MLC, CML, PLT and allogeneic suppression.

Authors:  G Pawelec; A Rehbein; C Müller; H H Sonneborn; P Wernet
Journal:  Immunology       Date:  1981-04       Impact factor: 7.397

2.  Responsiveness of germfree mice in mixed leukocyte culture. Reexamining the nature of the responding unit.

Authors:  M B Widmer; P M Sondel; F H Bach
Journal:  J Exp Med       Date:  1972-08-01       Impact factor: 14.307

3.  Nature of the stimulating cell in the syngeneic and the allogeneic mixed lymphocyte reaction in mice.

Authors:  H Von Boehmer; K Shortman; P Adams
Journal:  J Exp Med       Date:  1972-12-01       Impact factor: 14.307

4.  Clonal character of F1 hybrid lymphocyte subset recognition of parental cells in one-way mixed lymphocyte cultures.

Authors:  B M Gebhardt; Y Nakao; R T Smith
Journal:  J Exp Med       Date:  1974-08-01       Impact factor: 14.307

5.  Specific elimination of cytotoxic effector cells. I. Adsorptive behavior of effectors and their precursors and spleen cell monolayers.

Authors:  J R Neefe; D H Sachs
Journal:  J Exp Med       Date:  1976-10-01       Impact factor: 14.307

6.  Quantitative studies on the mixed lymphocyte interaction in rats. VI. Reactivity of lymphocytes from conventional and germfree rats to allogeneic and xenogeneic cell surface antigens.

Authors:  D B Wilson; D H Fox
Journal:  J Exp Med       Date:  1971-10-01       Impact factor: 14.307

7.  Tumor-secific immunity to chemically induced tumors. Evidence for immunologic specificity and shared antigenicity in lymphocyte responses to soluble tumor antigens.

Authors:  J T Frbes; Y Nakaw; R T Smith
Journal:  J Exp Med       Date:  1975-05-01       Impact factor: 14.307

8.  Cellular immunoabsorbents in transplantation immunity. Specific in vitro deletion and recovery of mouse lymphoid cells sensitized against allogeneic tumors.

Authors:  G Berke; R H Levey
Journal:  J Exp Med       Date:  1972-04-01       Impact factor: 14.307
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.