| Literature DB >> 510182 |
G C Wagner, L S Seiden, C R Schuster.
Abstract
Repeated administration of methamphetamine was found to cause long-term changes in caudate dopamine levels in the rat and guinea pig. Methamphetamine was administered twice a day for thirty days. Two weeks following the last injection, the animals were killed and brains assayed for catecholamine content. These long-term depletions of dopamine, when combined with similar observations previously reported in rhesus monkeys, indicate a species generality of the effects of methamphetamine on caudate dopamine levels.Entities:
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Year: 1979 PMID: 510182 DOI: 10.1016/0376-8716(79)90076-0
Source DB: PubMed Journal: Drug Alcohol Depend ISSN: 0376-8716 Impact factor: 4.492