Literature DB >> 50999

Cellular co-operation by mouse lymphocytes to chemically defined antigens.

J G Levy, B Kelly.   

Abstract

When populations of mouse spleen cells were treated with a highly radioactive 125I-labelled haptenic conjugate (125I-labelled PDG-N) and subsequently injected into X-irradiated, immunized (N-10-C) syngeneic BALB/c mice, it was found that after autoradiography with 125I-labelled N and C haptenic conjugates, the numbers of ABC to both the N and C haptens decreased. The number of ABC found were significantly lower than those found in mice that had been reconstituted with cells "suicided" with another 125I-labelled antigen (125I-labelled BSA) and subsequently immunized with N-10-C.

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Year:  1975        PMID: 50999      PMCID: PMC1445954     

Source DB:  PubMed          Journal:  Immunology        ISSN: 0019-2805            Impact factor:   7.397


  10 in total

1.  THE PREPARATION OF I-131-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY.

Authors:  F C GREENWOOD; W M HUNTER; J S GLOVER
Journal:  Biochem J       Date:  1963-10       Impact factor: 3.857

2.  The carrier effect in the secondary response to hapten-protein conjugates. II. Cellular cooperation.

Authors:  N A Mitchison
Journal:  Eur J Immunol       Date:  1971-01       Impact factor: 5.532

3.  Immunogenicity of macrophage-bound antigens: the requirement for hapten and carrier determinants to be on the same molecule for T and B lymphocyte collaboration.

Authors:  E R Unanue; D H Katz
Journal:  Eur J Immunol       Date:  1973-09       Impact factor: 5.532

4.  Immunological studies on the major haptenic peptides from performic acid oxidized ferredoxin from Clostridium pasteurianum.

Authors:  B Kelly; J G Levy
Journal:  Biochemistry       Date:  1971-05-11       Impact factor: 3.162

5.  Specific inactivation of thymus-derived (T) and non-thymus-derived (B) lymphocytes by 125I-labelled antigen.

Authors:  A Basten; J F Miller; N L Warner; J Pye
Journal:  Nat New Biol       Date:  1971-05-26

6.  Selective binding of chemically defined antigenic peptides to mouse lymphocytes.

Authors:  B Kelly; B Kaye; W Yoshizawa; J G Levy; D G Kilburn
Journal:  Eur J Immunol       Date:  1974-05       Impact factor: 5.532

7.  The effect of haptenic peptides from performic acid oxidized ferredoxin from Clostridium pasteurianum and protein carrier-hapten conjugates on the immune response of macrophages and lymphoid cells from animals immunized against oxidized ferredoxin.

Authors:  D Waterfield; J G Levy; D G Kilburn; R M Teather
Journal:  Cell Immunol       Date:  1972-02       Impact factor: 4.868

8.  Cell cooperation in antibody induction. The susceptibility of helper cells to specific lethal radioactive antigen.

Authors:  G E Roelants; B A Askonas
Journal:  Eur J Immunol       Date:  1971-06       Impact factor: 5.532

9.  Specific inactivation of antigen-reactive cells with 125I-labelled antigen.

Authors:  G L Ada; P Byrt
Journal:  Nature       Date:  1969-06-28       Impact factor: 49.962

10.  Deletion of hapten-binding cells by a highly radioactive 125-I conjugate.

Authors:  D T Golan; Y Borel
Journal:  J Exp Med       Date:  1972-08-01       Impact factor: 14.307

  10 in total

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