Literature DB >> 5099294

Equilibrium and rate constants for the interconversion of two conformations of -chymotrypsin. The existence of a catalytically inactive conformation at neutral p H.

A R Fersht, Y Requena.   

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Year:  1971        PMID： 5099294     DOI： 10.1016/0022-2836(71)90294-4

Source DB:  PubMed          Journal:  J Mol Biol        ISSN： 0022-2836            Impact factor:   5.469


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  27 in total

1.  Changes in the kinetic behaviour of threonine transport into Trypanosoma brucei elicited by variation in hydrogen ion concentration.

Authors:  H P Voorheis
Journal:  Biochem J       Date:  1977-04-15       Impact factor: 3.857

2.  A fluorescence stopped-flow kinetic study of the conformational activation of alpha-chymotrypsin and several mutants.

Authors:  Gert Verheyden; Janka Matrai; Guido Volckaert; Yves Engelborghs
Journal:  Protein Sci       Date:  2004-09       Impact factor: 6.725

3.  Kinetic analysis of the control through inhibition of autocatalytic zymogen activation.

Authors:  M C Manjabacas; E Valero; M García-Moreno; F García-Cánovas; J N Rodríguez; R Varón
Journal:  Biochem J       Date:  1992-03-01       Impact factor: 3.857

4.  Conformational selection or induced fit? A critical appraisal of the kinetic mechanism.

Authors:  Austin D Vogt; Enrico Di Cera
Journal:  Biochemistry       Date:  2012-07-16       Impact factor: 3.162

5.  Kinetic dissection of the pre-existing conformational equilibrium in the trypsin fold.

Authors:  Austin D Vogt; Pradipta Chakraborty; Enrico Di Cera
Journal:  J Biol Chem       Date:  2015-07-27       Impact factor: 5.157

6.  Stabilization of the E* form turns thrombin into an anticoagulant.

Authors:  Alaji Bah; Christopher J Carrell; Zhiwei Chen; Prafull S Gandhi; Enrico Di Cera
Journal:  J Biol Chem       Date:  2009-05-27       Impact factor: 5.157

7.  Exploration of the activation pathway of Deltaalpha-Chymotrypsin with molecular dynamics simulations and correlation with kinetic experiments.

Authors:  Janka Mátrai; Abel Jonckheer; Eddy Joris; Peter Krüger; Eric Carpenter; Jack Tuszynski; Marc De Maeyer; Yves Engelborghs
Journal:  Eur Biophys J       Date:  2008-08-27       Impact factor: 1.733

8.  Mutant N143P reveals how Na+ activates thrombin.

Authors:  Weiling Niu; Zhiwei Chen; Leslie A Bush-Pelc; Alaji Bah; Prafull S Gandhi; Enrico Di Cera
Journal:  J Biol Chem       Date:  2009-10-21       Impact factor: 5.157

9.  The unreliability of estimates of group dissociation constants.

Authors:  H B Dixon
Journal:  Biochem J       Date:  1976-03-01       Impact factor: 3.857

Review 10.  Serine proteases.

Authors:  Enrico Di Cera
Journal:  IUBMB Life       Date:  2009-05       Impact factor: 3.885
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