Literature DB >> 5098961

Reversible osmotic opening of the blood-brain barrier.

S I Rapoport, M Hori, I Klatzo.   

Abstract

Reversible breakdown of the blood-brain barrier is produced by a class of electrolytes and nonelectrolytes which have little or no lipid solubility but which difler in chemical and ionic properties. These agents may osmotically shrink barrier cells, possibly the vascular endothelium, and reversibly open spaces between them. Lipid-soluble nonelectrolytes damage the barrier irreversibly.

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Year:  1971        PMID： 5098961     DOI： 10.1126/science.173.4001.1026

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  21 in total

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5.  The clearance of urea and sucrose from isotonic and hypertonic fluids perfused through the ventriculo-cisternal system.

Authors:  C E Johanson; F M Foltz; A M Thompson
Journal:  Exp Brain Res       Date:  1974-04-30       Impact factor: 1.972

Review 6.  Intraarterial drug delivery for glioblastoma mutiforme: Will the phoenix rise again?

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7.  Modification of the blood-brain barrier: increased concentration and fate of enzymes entering the brain.

Authors:  J A Barranger; S I Rapoport; W R Fredericks; P G Pentchev; K D MacDermot; J K Steusing; R O Brady
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8.  Comparison of Endovascular and Intraventricular Gene Therapy With Adeno-Associated Virus-α-L-Iduronidase for Hurler Disease.

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9.  Vascular leakage through intraendothelial channels induced by cholera toxin in the skin of guinea pigs.

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Journal:  Am J Pathol       Date:  1974-04       Impact factor: 4.307

10.  A specific immunofluorescence technique for the demonstration of vasogenic brain edema in paraffin embedded material.

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Journal:  Acta Neuropathol       Date:  1979-01-12       Impact factor: 17.088
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