Bisalbuminaemia in a Spanish family: characterization of the albumin variant.

A case of bisalbuminaemia has been found in Luarca, Asturias. At least two relatives also bear the trait. The variant albumin Luarca (Al Lu, gene notation Al(Lu)), the first to be found on the mainland of Spain, is described in terms of its electrophoretic mobilities and dye-binding properties. It is heat-stable but sensitive to storage, freezing, and thawing and it is the first albumin to show this property.