Literature DB >> 5086393

Molecular structure of LSD.

R W Baker, C Chothia, P Pauling, H P Weber.   

Abstract

The molecular configuration of lysergic acid diethylamide (LSD) in crystals of the iodobenzoate has been determined by using x-ray diffraction techniques. The configuration shows strain and steric hindrance and the conformation is fixed. Some of the implications of this for the hallucinogenic activity of LSD are discussed.

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Year:  1972        PMID： 5086393     DOI： 10.1126/science.178.4061.614

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  2 in total

1.  Crystal Structure of an LSD-Bound Human Serotonin Receptor.

Authors:  Daniel Wacker; Sheng Wang; John D McCorvy; Robin M Betz; A J Venkatakrishnan; Anat Levit; Katherine Lansu; Zachary L Schools; Tao Che; David E Nichols; Brian K Shoichet; Ron O Dror; Bryan L Roth
Journal:  Cell       Date:  2017-01-26       Impact factor: 41.582

2.  The computational design of test compounds with potentially specific biological activity: histamine-H2 agonists derived from 5-HT/H2 antagonists.

Authors:  S Topiol; M Sabio
Journal:  J Comput Aided Mol Des       Date:  1991-06       Impact factor: 3.686
  2 in total

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