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Literature DB >> 5084817

The occurrence of tolerance to a central depressant effect of nicotine.

Abstract

1. Rats were injected with 0.8 mg nicotine/kg, 0.8 mg amphetamine/kg or with saline immediately before being tested for 30 min in activity boxes.2. During the first 3 trials the nicotine group were less active than the controls but from trial 5 onwards nicotine had a stimulant effect. The stimulant effect of the amphetamine did not alter with repeated injection.

Entities: Chemical Species

Mesh：

Substances：
Nicotine
Amphetamine

Year: 1972 PMID： 5084817 PMCID： PMC1666121 DOI： 10.1111/j.1476-5381.1972.tb06857.x

Source DB: PubMed Journal: Br J Pharmacol ISSN： 0007-1188 Impact factor: 8.739

5 in total

1. The measurement of the influence of drugs on voluntary activity in mice.

Authors: P B DEWS
Journal: Br J Pharmacol Chemother Date: 1953-03

2. Antagonism by antimuscarinic and ganglion-blocking drugs of some of the behavioural effects of nicotine.

Authors: C F Morrison; J M Goodyear; C M Sellers
Journal: Psychopharmacologia Date: 1969

3. The effects of nicotine on punished behaviour.

Authors: C F Morrison
Journal: Psychopharmacologia Date: 1969

4. The modification by physostigmine of some effects of nicotine on bar-pressing behaviour of rats.

Authors: C F Morrison
Journal: Br J Pharmacol Chemother Date: 1968-01

5. A comparison of the effects of nicotine and amphetamine on DRL performance in the rat.

Authors: C F Morrison
Journal: Psychopharmacologia Date: 1968

5 in total

37 in total

1. Sensitivity and tolerance to nicotine in smokers and nonsmokers.

Authors: E D Srivastava; M A Russell; C Feyerabend; J G Masterson; J Rhodes
Journal: Psychopharmacology (Berl) Date: 1991 Impact factor: 4.530

2. Effect of acute and subchronic nicotine treatment on cortical efflux of [3H]-D-aspartate and endogenous GABA in freely moving guinea-pigs.

Authors: L Beani; S Tanganelli; T Antonelli; L Ferraro; M Morari; P Spalluto; A Nordberg; C Bianchi
Journal: Br J Pharmacol Date: 1991-09 Impact factor: 8.739

3. Testing environment shape differentially modulates baseline and nicotine-induced changes in behavior: Sex differences, hypoactivity, and behavioral sensitization.

Authors: J M Illenberger; C F Mactutus; R M Booze; S B Harrod
Journal: Pharmacol Biochem Behav Date: 2017-12-19 Impact factor: 3.533

4. Acute and chronic tolerance to nicotine measured by activity in rats.

Authors: I P Stolerman; R Fink; M E Jarvik
Journal: Psychopharmacologia Date: 1973-06-29

5. Proceedings of the Fiftieth Anniversary Meeting of the British Pharmacological Society, University of Oxford, 16-18 September 1981. Abstracts.

Authors:
Journal: Br J Pharmacol Date: 1981-12 Impact factor: 8.739

The occurrence of tolerance to a central depressant effect of nicotine.

1. The measurement of the influence of drugs on voluntary activity in mice.

2. Antagonism by antimuscarinic and ganglion-blocking drugs of some of the behavioural effects of nicotine.

3. The effects of nicotine on punished behaviour.

4. The modification by physostigmine of some effects of nicotine on bar-pressing behaviour of rats.

5. A comparison of the effects of nicotine and amphetamine on DRL performance in the rat.

1. Sensitivity and tolerance to nicotine in smokers and nonsmokers.

2. Effect of acute and subchronic nicotine treatment on cortical efflux of [3H]-D-aspartate and endogenous GABA in freely moving guinea-pigs.

3. Testing environment shape differentially modulates baseline and nicotine-induced changes in behavior: Sex differences, hypoactivity, and behavioral sensitization.

4. Acute and chronic tolerance to nicotine measured by activity in rats.

5. Proceedings of the Fiftieth Anniversary Meeting of the British Pharmacological Society, University of Oxford, 16-18 September 1981. Abstracts.

6. Behavioural and neurochemical adaptations to nicotine in rats: influence of NMDA antagonists.

7. Nicotine increases alcohol self-administration and reinstates alcohol seeking in rats.

8. Effects of nicotine and d-amphetamine on intracranial self-stimulation in a shuttle box test in rats.

9. Characterization of the locomotor stimulant action of nicotine in tolerant rats.

10. Characteristics of tail-tremor induced by nicotine in rats.