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Literature DB >> 5084816

The effect of lithium salts on the urinary excretion of -oxoglutarate in man.

P A Bond, F A Jenner, C R Lee, E Lenton, R J Pollitt, G A Sampson.

Abstract

1. Lithium ions in therapeutic doses cause an increase in the renal excretion of alpha-oxoglutarate and glutaric acid.2. The excretion is probably due to reduced renal tubular reabsorption.3. Neither citrate, lactate nor pyruvate excretion rises.

Entities: Chemical Disease Gene Species

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Year: 1972 PMID： 5084816 PMCID： PMC1666115 DOI： 10.1111/j.1476-5381.1972.tb06854.x

Source DB: PubMed Journal: Br J Pharmacol ISSN： 0007-1188 Impact factor: 8.739

17 in total

1. RENAL HANDLING OF ALPHA-KETOGLUTARATE BY THE DOG.

Authors: S BALAGURA; R F PITTS
Journal: Am J Physiol Date: 1964-08

2. Renal utilization and excretion of alpha-ketoglutarate in dog: effect of alkalosis.

Authors: J J COHEN; E WITTMANN
Journal: Am J Physiol Date: 1963-05

3. A simplified method for the determination of citric acid.

Authors: E BEUTLER; M K YEH
Journal: J Lab Clin Med Date: 1959-07

4. Alkalosis in sodium and potassium depletion; with especial reference to organic acid excretion.

Authors: B M EVANS; I MACINTYRE; C R MACPHERSON; M D MILNE
Journal: Clin Sci Date: 1957-02 Impact factor: 6.124

5. Prophylactic lithium in affective disorders. Controlled trial.

Authors: A Coppen; R Noguera; J Bailey; B H Burns; M S Swani; E H Hare; R Gardner; R Maggs
Journal: Lancet Date: 1971-08-07 Impact factor: 79.321

6. Prophylactic lithium: double blind discontinuation in manic-depressive and recurrent-depressive disorders.

Authors: P C Baastrup; J C Poulsen; M Schou; K Thomsen; A Amdisen
Journal: Lancet Date: 1970-08-15 Impact factor: 79.321

7. Uric-acid metabolism in manic-depressive illness and during lithium therapy.

Authors: A Anumonye; H W Reading; F Knight; G W Ashcroft
Journal: Lancet Date: 1968-06-15 Impact factor: 79.321

8. Renal tubular secretion of p-aminohippurate in the dog: effects of alpha-ketoglutarate.

Authors: S Balagura-Baruch; W J Stone
Journal: Nephron Date: 1969 Impact factor: 2.847

9. An improved method for the determination of homovanillic acid and vanilmandelic acid by gas chromatography.

Authors: T J Sprinkle; A H Porter; M Greer; C M Williams
Journal: Clin Chim Acta Date: 1969-09 Impact factor: 3.786

10. Effects of LI + on the metabolism in brain of glutamate, glutamine, aspartate and GABA from (1- 14 C)acetate in vitro.

Authors: S Berl; D D Clarke
Journal: Brain Res Date: 1972-01-14 Impact factor: 3.252

9 in total

The effect of lithium salts on the urinary excretion of -oxoglutarate in man.

1. RENAL HANDLING OF ALPHA-KETOGLUTARATE BY THE DOG.

2. Renal utilization and excretion of alpha-ketoglutarate in dog: effect of alkalosis.

3. A simplified method for the determination of citric acid.

4. Alkalosis in sodium and potassium depletion; with especial reference to organic acid excretion.

5. Prophylactic lithium in affective disorders. Controlled trial.

6. Prophylactic lithium: double blind discontinuation in manic-depressive and recurrent-depressive disorders.

7. Uric-acid metabolism in manic-depressive illness and during lithium therapy.

8. Renal tubular secretion of p-aminohippurate in the dog: effects of alpha-ketoglutarate.

9. An improved method for the determination of homovanillic acid and vanilmandelic acid by gas chromatography.

10. Effects of LI + on the metabolism in brain of glutamate, glutamine, aspartate and GABA from (1- 14 C)acetate in vitro.

1. Role of isoleucine-554 in lithium binding by the Na+/dicarboxylate cotransporter NaDC1.

2. Urinary dicarboxylic acids in patients receiving lithium or rubidium salts.

3. Reabsorption of dicarboxylic acids from the proximal convolution of rat kidney.

4. Interactions between lithium and renal transport of Krebs cycle intermediates.

5. The effect of lithium and related metal ions on the urinary excretion of 2-oxoglutarate and citrate in the rat.

6. Human sodium-coupled citrate transporter, the orthologue of Drosophila Indy, as a novel target for lithium action.

7. Sodium-dependent dicarboxylate transport in rat renal basolateral membrane vesicles.

8. Effects of chronic lithium administration on renal acid excretion in humans and rats.

9. Consequences of NaCT/SLC13A5/mINDY deficiency: good versus evil, separated only by the blood-brain barrier.