Literature DB >> 508132

Trial of baclofen in amyotrophic lateral sclerosis.

F H Norris, K S U, B Sachais, M Carey.   

Abstract

A trial of the antispastic drug baclofen was made in amyotrophic lateral sclerosis. Some patients noted reduction of tonus and spasticity; but others had no benefit, nor was the course of the disease altered by long-term administration of baclofen. No major side effects occurred.

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Year:  1979        PMID： 508132     DOI： 10.1001/archneur.1979.00500470085019

Source DB:  PubMed          Journal:  Arch Neurol        ISSN： 0003-9942


  8 in total

1.  A randomized trial of mexiletine in ALS: Safety and effects on muscle cramps and progression.

Authors:  Michael D Weiss; Eric A Macklin; Zachary Simmons; Angela S Knox; David J Greenblatt; Nazem Atassi; Michael Graves; Nicholas Parziale; Johnny S Salameh; Colin Quinn; Robert H Brown; Jane B Distad; Jaya Trivedi; Jeremy M Shefner; Richard J Barohn; Alan Pestronk; Andrea Swenson; Merit E Cudkowicz
Journal:  Neurology       Date:  2016-02-24       Impact factor: 9.910

Review 2.  Gamma aminobutyric acid (GABA) modulators for amyotrophic lateral sclerosis/motor neuron disease.

Authors:  Andrea Diana; Rita Pillai; Paolo Bongioanni; Aidan G O'Keeffe; Robert G Miller; Dan H Moore
Journal:  Cochrane Database Syst Rev       Date:  2017-01-09

3.  Associations between co-medications and survival in ALS-a cohort study from Austria.

Authors:  Hakan Cetin; Uros Klickovic; Jakob Rath; Gudrun Zulehner; Judith Füzi; Berthold Reichardt; Michael Hagmann; Julia Wanschitz; Wolfgang N Löscher; Eduard Auff; Fritz Zimprich
Journal:  J Neurol       Date:  2015-05-10       Impact factor: 4.849

Review 4.  Management of amyotrophic lateral sclerosis.

Authors:  Philippe Corcia; Vincent Meininger
Journal:  Drugs       Date:  2008       Impact factor: 9.546

5.  Is distal motor and/or sensory demyelination a distinctive feature of anti-MAG neuropathy?

Authors:  Pierre Lozeron; Vincent Ribrag; David Adams; Marion Brisset; Marguerite Vignon; Marine Baron; Marion Malphettes; Marie Theaudin; Bertrand Arnulf; Nathalie Kubis
Journal:  J Neurol       Date:  2016-06-17       Impact factor: 4.849

Review 6.  A comprehensive review of amyotrophic lateral sclerosis.

Authors:  Sara Zarei; Karen Carr; Luz Reiley; Kelvin Diaz; Orleiquis Guerra; Pablo Fernandez Altamirano; Wilfredo Pagani; Daud Lodin; Gloria Orozco; Angel Chinea
Journal:  Surg Neurol Int       Date:  2015-11-16

7.  Voxel-based mapping of grey matter volume and glucose metabolism profiles in amyotrophic lateral sclerosis.

Authors:  M-S Buhour; F Doidy; A Mondou; A Pélerin; L Carluer; F Eustache; F Viader; B Desgranges
Journal:  EJNMMI Res       Date:  2017-03-06       Impact factor: 3.138

8.  Longitudinal grey matter and metabolic contributions to cognitive changes in amyotrophic lateral sclerosis.

Authors:  Thomas Hinault; Shailendra Segobin; Soumia Benbrika; Laurence Carluer; Franck Doidy; Francis Eustache; Fausto Viader; Béatrice Desgranges
Journal:  Brain Commun       Date:  2022-09-07
  8 in total

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