Literature DB >> 5076907

Acrylamide polymerization: new method for determining the oxygen content in blood.

J Folkman, H Conn, R Harmel.   

Abstract

A new principle for determining the oxygen content of 0.1-milliliter blood samples has been developed, based on measurement of the delay in gelation during copolymerization of acrylamide and bisacrylamide initiated by free radicals. The logarithm of this time interval is linearly proportional to the oxygen content of the blood sample over the range 0 to 22 milliliters of oxygen per 100 milliliters of whole blood. Physiological variations of pH and pCO(2) do not affect the sensitivity of the assay.

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Year:  1972        PMID: 5076907     DOI: 10.1126/science.178.4057.170

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  2 in total

1.  Collateral vessel formation: isolation of a transferable factor promoting a vascular response.

Authors:  J T Cuttino; R J Bartrum; N K Hollenberg; H L Abrams
Journal:  Basic Res Cardiol       Date:  1975 Sep-Oct       Impact factor: 17.165

2.  Oxygen content determined by acrylamide polymerization: screening of anticancer agents, generation of oxyhemoglobin dissociation curves, and potential applications.

Authors:  D Tapper; R S Langer; H Conn; J Folkman
Journal:  Ann Surg       Date:  1979-03       Impact factor: 12.969

  2 in total

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