Literature DB >> 5072337

Triptolide and tripdiolide, novel antileukemic diterpenoid triepoxides from Tripterygium wilfordii.

S M Kupchan, W A Court, R G Dailey, C J Gilmore, R F Bryan.   

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Year:  1972        PMID： 5072337     DOI： 10.1021/ja00775a078

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


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  97 in total

1.  Inhibition of tumor cellular proteasome activity by triptolide extracted from the Chinese medicinal plant 'thunder god vine'.

Authors:  Li Lu; Jyoti Kanwar; Sara Schmitt; Qiuzhi Cindy Cui; Chuanyin Zhang; Cong Zhao; Q Ping Dou
Journal:  Anticancer Res       Date:  2011-01       Impact factor: 2.480

2.  XPB, a subunit of TFIIH, is a target of the natural product triptolide.

Authors:  Denis V Titov; Benjamin Gilman; Qing-Li He; Shridhar Bhat; Woon-Kai Low; Yongjun Dang; Michael Smeaton; Arnold L Demain; Paul S Miller; Jennifer F Kugel; James A Goodrich; Jun O Liu
Journal:  Nat Chem Biol       Date:  2011-01-30       Impact factor: 15.040

3.  NF-κB inhibition significantly upregulates the norepinephrine transporter system, causes apoptosis in pheochromocytoma cell lines and prevents metastasis in an animal model.

Authors:  Karel Pacak; Marta Sirova; Alessio Giubellino; Lubomira Lencesova; Lucia Csaderova; Marcela Laukova; Sona Hudecova; Olga Krizanova
Journal:  Int J Cancer       Date:  2012-08-20       Impact factor: 7.396

4.  Identification and functional characterization of diterpene synthases for triptolide biosynthesis from Tripterygium wilfordii.

Authors:  Ping Su; Hongyu Guan; Yujun Zhao; Yuru Tong; Meimei Xu; Yifeng Zhang; Tianyuan Hu; Jian Yang; Qiqing Cheng; Linhui Gao; Yujia Liu; Jiawei Zhou; Reuben J Peters; Luqi Huang; Wei Gao
Journal:  Plant J       Date:  2017-12-02       Impact factor: 6.417

5.  Role of reactive oxygen species in triptolide-induced apoptosis of renal tubular cells and renal injury in rats.

Authors:  Fan Yang; Luo Zhuo; Sunnassee Ananda; Tingyi Sun; Shangxun Li; Liang Liu
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2011-06-14

6.  PG490-88, a derivative of triptolide, blocks bleomycin-induced lung fibrosis.

Authors:  G Krishna; K Liu; H Shigemitsu; M Gao; T A Raffin; G D Rosen
Journal:  Am J Pathol       Date:  2001-03       Impact factor: 4.307

7.  A characterization of the activity of alpha-1,3,5-triglycidyl-s-triazinetrione, a novel antineoplastic compound.

Authors:  F Spreafico; G Atassi; S Filippeschi; C Malfiore; S Noseda; D Boschetti
Journal:  Cancer Chemother Pharmacol       Date:  1980       Impact factor: 3.333

8.  Triptolide induces anti-inflammatory cellular responses.

Authors:  Ranyia Matta; Xianxi Wang; Hui Ge; William Ray; Leif D Nelin; Yusen Liu
Journal:  Am J Transl Res       Date:  2009-03-05       Impact factor: 4.060

9.  Triptolide induces Sertoli cell apoptosis in mice via ROS/JNK-dependent activation of the mitochondrial pathway and inhibition of Nrf2-mediated antioxidant response.

Authors:  Yu Wang; Su-Han Guo; Xue-Jun Shang; Li-Sha Yu; Jian-Wei Zhu; Ang Zhao; Yan-Fen Zhou; Guo-Hua An; Qi Zhang; Bo Ma
Journal:  Acta Pharmacol Sin       Date:  2017-09-14       Impact factor: 6.150

10.  Synergistic effect of triptolide combined with 5-fluorouracil on colon carcinoma.

Authors:  Xiao-yan Tang; You-qing Zhu; Wen-hui Tao; Bai Wei; Xiao-ling Lin
Journal:  Postgrad Med J       Date:  2007-05       Impact factor: 2.401
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