Literature DB >> 507098

Altered collagen composition in a prolapsing mitral valve with ruptured chordae tendineae.

D Hammer, C V Leier, N Baba, J S Vasko, C F Wooley, S R Pinnell.   

Abstract

A patient presented with mitral valve prolapse, ruptured chordae tendineae, severe mitral regurgitation and congestive heart failure. Pathologic studies demonstrated myxomatous changes of both mitral leaflets. Collagen analysis of the valve and of the chordae tendineae revealed the presence of type I collagen in normal quantities and a striking absence of type III and AB collagens. The altered collagen in this patient's mitral valve probably contributed to the development of his mitral valve disorder.

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Year:  1979        PMID： 507098     DOI： 10.1016/0002-9343(79)90746-0

Source DB:  PubMed          Journal:  Am J Med        ISSN： 0002-9343            Impact factor:   4.965


  14 in total

Review 1.  The impairment of lysyl oxidase in keratoconus and in keratoconus-associated disorders.

Authors:  Lubica Dudakova; Katerina Jirsova
Journal:  J Neural Transm (Vienna)       Date:  2013-02-20       Impact factor: 3.575

Review 2.  Mitral valve prolapse associated with other disorders. Casual coincidence, common link, or fundamental genetic disturbance?

Authors:  A D Malcolm
Journal:  Br Heart J       Date:  1985-04

3.  Collagen composition of normal and myxomatous human mitral heart valves.

Authors:  W G Cole; D Chan; A J Hickey; D E Wilcken
Journal:  Biochem J       Date:  1984-04-15       Impact factor: 3.857

4.  Type I collagen content is increased in lungs of patients with adult respiratory distress syndrome.

Authors:  J A Last; A D Siefkin; K M Reiser
Journal:  Thorax       Date:  1983-05       Impact factor: 9.139

5.  Mitral valve prolapse, aortic compliance, and skin collagen in joint hypermobility syndrome.

Authors:  C E Handler; A Child; N D Light; D E Dorrance
Journal:  Br Heart J       Date:  1985-11

6.  Prevalence of mitral valve prolapse in keratoconus patients.

Authors:  K W Sharif; T A Casey; J Coltart
Journal:  J R Soc Med       Date:  1992-08       Impact factor: 5.344

7.  Quantitative structural analysis of collagen in chordae tendineae and its relation to floppy mitral valves and proteoglycan infiltration.

Authors:  P Whittaker; D R Boughner; D G Perkins; P B Canham
Journal:  Br Heart J       Date:  1987-03

8.  Genetic evidence that mutations in the COL1A1, COL1A2, COL3A1, or COL5A2 collagen genes are not responsible for mitral valve prolapse.

Authors:  A M Henney; P Tsipouras; R C Schwartz; A H Child; R B Devereux; G J Leech
Journal:  Br Heart J       Date:  1989-03

9.  Biochemical characterization of individual normal, floppy and rheumatic human mitral valves.

Authors:  Y Lis; M C Burleigh; D J Parker; A H Child; J Hogg; M J Davies
Journal:  Biochem J       Date:  1987-06-15       Impact factor: 3.857

10.  Collagen organization in canine myxomatous mitral valve disease: an x-ray diffraction study.

Authors:  Mojtaba Hadian; Brendan M Corcoran; Richard I Han; J Günter Grossmann; Jeremy P Bradshaw
Journal:  Biophys J       Date:  2007-06-08       Impact factor: 4.033
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