Literature DB >> 5061904

Ovulation in hamster: induction by subunit of ovine interstitial cell stimulating hormone.

W H Yang, M R Sairam, H Papkoff, C H Li.   

Abstract

As little as 5 micrograms of interstitial cell stimulating hormone (ICSH) or 20 micrograms of ICSH-beta is effective for the induction of ovulation in 100 percent of hamsters treated at 0500 hours on day 4 after lordosis, whereas as much as 800 micrograms of ICSH-alpha is ineffective. Both ICSH and ICSH-beta are also effective for induction of ovulation in hypophysectomized animals. Thus, the ovulation-inducing activity of the ICSH molecule resides in its beta subunit.

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Year:  1972        PMID: 5061904     DOI: 10.1126/science.175.4022.637

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  4 in total

1.  Recognition of the beta-subunit of human chorionic gonadotropin and sub-determinants by target tissue receptors.

Authors:  S Ramakrishnan; C Das; G P Talwar
Journal:  Biochem J       Date:  1978-11-15       Impact factor: 3.857

2.  Beta subunits of human choriogonadotropin and ovine lutropin are biologically active.

Authors:  N R Moudgal; C H Li
Journal:  Proc Natl Acad Sci U S A       Date:  1982-04       Impact factor: 11.205

3.  Ability of human chorionic gonadotropin beta-subunit to inhibit the steroidogenic response to lutropin.

Authors:  R R Dighe; K Muralidhar; N R Moudgal
Journal:  Biochem J       Date:  1979-06-15       Impact factor: 3.857

4.  Studies on rat ovarian receptors for lutropin (luteinizing hormone). Interaction with beta-subunit of sheep lutropin.

Authors:  K Muralidhar; N R Moudgal
Journal:  Biochem J       Date:  1976-12-15       Impact factor: 3.857

  4 in total

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