Literature DB >> 5060670

Plasminogen activator in bile during extracorporeal perfusion of pig liver.

A Jedrychowski, S P Parbhoo, P Hillenbrand.   

Abstract

Plasminogen activator activity was studied in bile and perfusate during extracorporeal pig liver perfusion. Plasminogen activator activity in bile was up to 58 times greater than in perfusate. A high level of plasminogen activator activity in bile was also found after the addition of urokinase to the perfusate. These results suggest that bile is the main route of active excretion of plasminogen activator and urokinase from the liver in experimental liver perfusion.

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Year:  1972        PMID： 5060670      PMCID： PMC1411971          DOI： 10.1136/gut.13.1.54

Source DB:  PubMed          Journal:  Gut        ISSN： 0017-5749            Impact factor:   23.059


  7 in total

1.  ABNORMAL PLASMINOGEN-PLASMIN SYSTEM ACTIVITY (FIBRINOLYSIS) IN PATIENTS WITH HEPATIC CIRRHOSIS: ITS CAUSE AND CONSEQUENCES.

Authors:  A P FLETCHER; O BIEDERMAN; D MOORE; N ALKJAERSIG; S SHERRY
Journal:  J Clin Invest       Date:  1964-04       Impact factor: 14.808

2.  Non-enzymatic lysis of fibrin s by bile.

Authors:  W H FLEMING; P S NORMAN
Journal:  Proc Soc Exp Biol Med       Date:  1960 Aug-Sep

3.  On plasma fibrinolytic activity in cryptogenetic splenomegaly.

Authors:  H C KWAAN; A J MCFADZEAN; J COOK
Journal:  Scott Med J       Date:  1957-04       Impact factor: 0.729

4.  [A plasminogen activator found in bile].

Authors:  S Hata
Journal:  Nihon Seirigaku Zasshi       Date:  1967

5.  Plasminogen activator in bile stimulated by sodium taurocholate in isolated hamster livers.

Authors:  S Oshiba; L J Schoenfield
Journal:  Proc Soc Exp Biol Med       Date:  1970-01

6.  Estimation of the activator of fibrinolysis by means of the euglobulin test.

Authors:  T Januszko; L Dubińska
Journal:  Acta Med Pol       Date:  1965

7.  Extracorporeal pig-liver perfusoon in treatment of hepatic coma due to fulminant hepatitis.

Authors:  S P Parbhoo; I M James; A Ajdukiewicz; C Xanalatos; J Kennedy; L J Chalstrey; P J Brock; P Sayer; S Sherlock
Journal:  Lancet       Date:  1971-04-03       Impact factor: 79.321
  7 in total

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