| Literature DB >> 5059567 |
F A Oski, L D Miller, M Delivoria-Papadopoulos, J H Manchester, J C Shelburn.
Abstract
Propranolol, a blocking agent for the beta adrenergic receptor, produces a redistribution of 2,3-diphosphoglycerate in the red cell. At concentrations of 3.3 x10(-5)M, 2,3-diphosphoglycerate in the red cell membrane becomes unbound in vitro. The administration of propranolol to hunmns produces similar changes and results in a decrease in the affinity of hemoglobin for oxygen.Entities:
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Year: 1972 PMID： 5059567 DOI： 10.1126/science.175.4028.1372
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728